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Titolo:
Comparison of serum concentrations of alpha-tocopherol and beta-carotene in a cross-sectional sample of obese and nonobese children (NHANES III)
Autore:
Strauss, RS;
Indirizzi:
UnivnterolADent New Jersey, Robert Wood Johnson Med Sch, Div Pediat Gastroe Univ Med & Dent New Jersey New Brunswick NJ USA 08903 Div Pediat Gastroe
Titolo Testata:
JOURNAL OF PEDIATRICS
fascicolo: 2, volume: 134, anno: 1999,
pagine: 160 - 165
SICI:
0022-3476(199902)134:2<160:COSCOA>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
LOW-DENSITY-LIPOPROTEIN; CORONARY HEART-DISEASE; VITAMIN-E CONSUMPTION; FOLLOW-UP; CARDIOVASCULAR-DISEASE; PLASMA-CONCENTRATIONS; LIPID-LEVELS; OVERWEIGHT; OXIDATION; WOMEN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Strauss, RS UnivnterolN-19, New Jersey, Robert Wood Johnson Med Sch, Div Pediat Gastroe Univ Med & Dent New Jersey 1 Robert Wood Johnson Pl,CN-19 NewBrunswick NJ USA 08903
Citazione:
R.S. Strauss, "Comparison of serum concentrations of alpha-tocopherol and beta-carotene in a cross-sectional sample of obese and nonobese children (NHANES III)", J PEDIAT, 134(2), 1999, pp. 160-165

Abstract

Introduction: Low intake of the fat-soluble antioxidants alpha-toropherol and beta-carotene has been linked to greater risks of cardiovascular disease in epidemiologic studies. Obesity in adults is associated with lower levels or alpha-tocopherol and beta-carotene, which may contribute to the increased risk of cardiovascular disease associated with obesity. Aim: To examine serum concentrations of beta-soluble antioxidants in a large, nationally representative sample of obese and nonobese children. Methods: Serum levels of alpha-tocopherol and beta-carotene were measured in 6139 children between the ages of 6 and 19 years enrolled in the National Health and Examination Survey, cycle III. Serum alpha-tocopherol levels were adjusted for fasting cholesterol and triglyceride levels. Nutritional intake was assessed by 24-hour dietary recall and food frequency questionnaires. Results: Serum levels of beta-carotene were significantly lower in obese children compared with those found in normal weight children (0.22 +/- 0.14 mu mol/L vs 0.29 +/- 0.1.7 mu mol/L, P < .001). After adjustment was done for serum triglyceride and cholesterol levels, alpha-tocopherol levels were also significantly lower in obese children (2.68 +/- 0.59 vs 3.17 +/- 0.60,P < .001). Approximately one half of obese children had serum levels of beta-carotene and adjusted alpha-tocopherol in the lowest quartile compared with approximately one quarter of normal weight children (P < .001). No significant differences were seen in reported intake of beta-carotene, alpha-tocopherol, fruit, or vegetables between obese and nonobese children. Conclusion: Reduced serum levels of fat-soluble antioxidants are present in obese children.

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Documento generato il 02/10/20 alle ore 01:33:20