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Titolo:
Ameliorating effects of water-soluble polysaccharides from woody ear (Auricularia auricula-judae Quel.) in genetically diabetic KK-A(y) mice
Autore:
Yuan, ZM; He, PM; Takeuchi, H;
Indirizzi:
Shizuoka Univ, Fac Agr, Dept Appl Biol Chem, Shizuoka 4228529, Japan Shizuoka Univ Shizuoka Japan 4228529 Biol Chem, Shizuoka 4228529, Japan Gifu Univ, United Grad Sch Agr Sci, Gifu 5011193, Japan Gifu Univ Gifu Japan 5011193 nited Grad Sch Agr Sci, Gifu 5011193, Japan
Titolo Testata:
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
fascicolo: 6, volume: 44, anno: 1998,
pagine: 829 - 840
SICI:
0301-4800(199812)44:6<829:AEOWPF>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOOD RESTRICTION; METABOLIC CONTROL; GLUCOSE; CARBOHYDRATE; FIBER; INSULIN; RATS; GUAR; DIET;
Keywords:
Auricularia auricula-judae Quel.; water-soluble polysaccharides; KK-A(y) mice; hypoglycemic effect;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Yuan, ZM Shizuoka Univ, Fac Agr, Dept Appl Biol Chem, Shizuoka 4228529, Japan Shizuoka Univ Shizuoka Japan 4228529 m, Shizuoka 4228529, Japan
Citazione:
Z.M. Yuan et al., "Ameliorating effects of water-soluble polysaccharides from woody ear (Auricularia auricula-judae Quel.) in genetically diabetic KK-A(y) mice", J NUTR SC V, 44(6), 1998, pp. 829-840

Abstract

We investigated the ameliorating effects of the three groups of water-soluble polysaccharides, a mixture of crude polysaccharides (FA), acidic polysaccharide fractions (FA-A), and neutral polysaccharide fractions (FA-N), obtained from the hot water extracts of the fruit bodies of Auricularia auricula-judae Quel, in genetically diabetic KK-AY mice from 6 to 11 weeks of age. Male mice were divided into five dietary groups: 1) control group, given a basal diet; 2) FA group, given an FA diet (15 g FA/kg diet); 3) FA-A group, given an FA-A diet (8 g FA-A/kg diet); 4) low FA-N group, given a low FA-N diet (2 g FA-N/kg diet); and 5) high FA-N group, given a high FA-N diet (8 g FA-N/kg diet). Compared with the control diet, FA supplementation had significant effects in lowering fasting and nonfasting blood glucose, HbA(1c), urinary glucose, food intake, and water intake. FA administration also improved glucose tolerance to intraperitoneal glucose loading, but it did not affect the nonfasting insulin level. FA-N supplementation had dose-dependent effects in lowering fasting and nonfasting blood glucose, insulin, HbA(1c), urinary glucose, food intake, and water intake. However, the glucose tolerance was not ameliorated by either the low or the high FA-N diet. FA-Aadministration showed no beneficial effects in KK-A(y) mice.

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Documento generato il 01/12/20 alle ore 18:40:27