Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Risk factors for cirrhosis in early stage alcoholic liver disease.
Autore:
Giraud, V; Naveau, S; Balian, A; Belda, E; Capron, F; Lemaigre, G; Chaput, JC;
Indirizzi:
Hop Antoine Beclere, Serv Hepatogastroenterol, F-92141 Clamart, France HopAntoine Beclere Clamart France F-92141 erol, F-92141 Clamart, France Hop Antoine Beclere, Serv Anat & Cytol Pathol, F-92141 Clamart, France HopAntoine Beclere Clamart France F-92141 thol, F-92141 Clamart, France
Titolo Testata:
GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE
fascicolo: 12, volume: 22, anno: 1998,
pagine: 997 - 1002
SICI:
0399-8320(199812)22:12<997:RFFCIE>2.0.ZU;2-C
Fonte:
ISI
Lingua:
FRE
Soggetto:
NATURAL-HISTORY; PERIVENULAR FIBROSIS; LIPID-PEROXIDATION; HEPATITIS; SEX; PROGRESSION; STEATOSIS; INJURY; ABUSE;
Keywords:
risk factors; alcoholic cirrhosis; fatty liver; female sex;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Giraud, V Hop92141ine Beclere, Serv Hepatogastroenterol, 157 Rue Porte de Trivaux, F- Hop Antoine Beclere 157 Rue Porte de Trivaux Clamart France F-92141
Citazione:
V. Giraud et al., "Risk factors for cirrhosis in early stage alcoholic liver disease.", GASTRO CL B, 22(12), 1998, pp. 997-1002

Abstract

Objective. - To assess the risk factors of cirrhosis in early stage alcoholic liver disease. Patients. - We investigated 83 heavy drinkers (60 males and 23 females) inwhom the first of two liver biopsies showed normal or pure alcoholic fattyliver. Results. - When the six following variables: sex, age, delay between the first and last biopsy, total duration of alcohol consumption before the first biopsy, daily alcohol consumption for the last 5 years before the first biopsy and the extent of fatty liver in the first biopsy, were considered together in stepwise regression analysis, the delay between the first and last biopsy (P < 0.0001), sex (P < 0.04) and the extent of fatty liver in the first biopsy (P < 0.06) significantly improved the prediction of cirrhosis. The odds ratio of cirrhosis for a women was 19.1 (confidence interval 95 %[1.85-197]). The odds ratio for cirrhosis for a percentage of fatty liver greater than or equal to 5/10 was 7.4 (confidence interval 95 % [1-92]). Conclusion. - With the same delay between two liver biopsies, the female sex and the extent of fatty liver are two independent risk factors for the development of cirrhosis in heavy drinkers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 05:58:00