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Titolo:
Near-infrared spectroscopy monitored cerebral venous thrombolysis
Autore:
Witham, TF; Nemoto, EM; Jungreis, CA; Kaufmann, AM;
Indirizzi:
Univ Pittsburgh, Sch Med, Dept Neurol Surg, Pittsburgh, PA 15261 USA Univ Pittsburgh Pittsburgh PA USA 15261 ol Surg, Pittsburgh, PA 15261 USA Univ Pittsburgh, Sch Med, Div Neuroradiol, Pittsburgh, PA 15261 USA Univ Pittsburgh Pittsburgh PA USA 15261 oradiol, Pittsburgh, PA 15261 USA Univ Calgary, Dept Clin Neurosci, Calgary, AB, Canada Univ Calgary Calgary AB Canada , Dept Clin Neurosci, Calgary, AB, Canada
Titolo Testata:
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
fascicolo: 1, volume: 26, anno: 1999,
pagine: 48 - 52
SICI:
0317-1671(199902)26:1<48:NSMCVT>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACTIVATED PROTEIN-C; DURAL SINUS THROMBOSIS; POOR ANTICOAGULANT RESPONSE; COAGULATION-FACTOR-V; INTRACRANIAL HEMATOMAS; PRETERM INFANTS; MUTATION; RESISTANCE; LEIDEN; THROMBOPHILIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Kaufmann, AM Foothills Hosp, Dept Clin Neurosci, 12th Floor,1403-29th St NW, Calgary, AB Foothills Hosp 12th Floor,1403-29th St NW Calgary AB Canada T2N 2T9
Citazione:
T.F. Witham et al., "Near-infrared spectroscopy monitored cerebral venous thrombolysis", CAN J NEUR, 26(1), 1999, pp. 48-52

Abstract

Background: Cerebral venous thrombosis is a clinical entity which is readily diagnosed with the advent of modern imaging techniques. Anticoagulation is now a standard therapy, but more recent treatment strategies have included endovascular thrombolysis. While the endpoint of this intervention both clinically and radiographically has not been defined, noninvasive monitoring techniques may add further objective measures of treatment response. Clinical Presentation: We present a patient with a four day history of worsening headache and papilledema on exam. Superior sagittal, straight, and bilateral transverse sinus thromboses were identified on computed tomography and angiography. Intervention: Emergent endovascular thrombolysis by a transvenous approach re-established venous patency and resulted in immediate resolution of the patient's symptoms. Cerebral oximetry by near-infrared spectroscopy was utilized during the procedure, and changes in chromophore concentrations correlated directly with angiographic and clinical resolution of thethrombosis. Conclusion: Near-infrared spectroscopy can provide continuous feedback during thrombolytic therapy in cerebral venous thrombosis and may help define endpoints of such intervention.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 16:12:25