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Titolo:
Risk of a new benzodiazepine prescription in relation to recent hospitalization
Autore:
Grad, R; Tamblyn, R; Holbrook, AM; Hurley, J; Feightner, J; Gayton, D;
Indirizzi:
McGill Univ, Montreal, PQ H3A 2T5, Canada McGill Univ Montreal PQ Canada H3A 2T5 Univ, Montreal, PQ H3A 2T5, Canada Royal Victoria Hosp, Montreal, PQ H3A 1A1, Canada Royal Victoria Hosp Montreal PQ Canada H3A 1A1 ntreal, PQ H3A 1A1, Canada McMaster Univ, Hamilton, ON L8S 4L8, Canada McMaster Univ Hamilton ON Canada L8S 4L8 iv, Hamilton, ON L8S 4L8, Canada St Josephs Hosp, Ctr Evaluat Med, Hamilton, ON, Canada St Josephs Hosp Hamilton ON Canada Ctr Evaluat Med, Hamilton, ON, Canada Univ Western Ontario, London, ON, Canada Univ Western Ontario London ON Canada estern Ontario, London, ON, Canada
Titolo Testata:
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
fascicolo: 2, volume: 47, anno: 1999,
pagine: 184 - 188
SICI:
0002-8614(199902)47:2<184:ROANBP>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC DISEASE SCORE; AUTOMATED PHARMACY DATA; PSYCHOTROPIC-DRUG USE; ELDERLY PATIENTS; HIP FRACTURE; COMMUNITY; MEDICATION; DATABASES; ILLNESS; QUEBEC;
Keywords:
benzodiazepines; hospitalization; aged; drug utilization; risk;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Grad, R McGill Univ, Montreal, PQ H3A 2T5, Canada McGill Univ Montreal PQCanada H3A 2T5 ntreal, PQ H3A 2T5, Canada
Citazione:
R. Grad et al., "Risk of a new benzodiazepine prescription in relation to recent hospitalization", J AM GER SO, 47(2), 1999, pp. 184-188

Abstract

OBJECTIVE: To determine if recent hospital admission was associated with new outpatient prescribing of benzodiazepines among community-dwelling olderpeople. DESIGN: Nested case-control study using administrative data sets of the provincial health insurance board. SETTING: Province of Quebec. PARTICIPANTS: Cases were 4127 community-dwelling older people who were newly dispensed a benzodiazepine during an g-month period in 1990. Controls were 16,486 community-dwelling older people who were dispensed any drug (except a benzodiazepine) on the same day as the case-defining index prescription. EXPOSURE AND OUTCOME MEASURES: Admission to an acute care hospital within a 30-day period before a new dispensing of a benzodiazepine. Other variables measured were patient age, gender, number of ambulatory physician visits,healthcare region, Chronic Disease Score (CDS), and use of drugs for depression and psychosis. RESULTS: Cases were more than three times as likely as controls to have been hospitalized in the 30-day period before the index date (adjusted odds ratio (OR) 3.09; 95% CI, 2.78-3.45). The use of prescription drugs for physical health problems modified this association in that cases who used more medication were also more likely to receive a new benzodiazepine prescription following a recent hospital admission (adjusted OR 4.09; 95% CI, 3.59-4.65 when the CDS was equal to 5 vs adjusted OR 1.96; 95% CI, 1.66-2.31 when the CDS was equal to 0). CONCLUSIONS: Recent hospitalization confers an increased risk of a new outpatient benzodiazepine prescription among community-dwelling older people in Quebec. Those who use more medication, and who may be more vulnerable to drug-related adverse events, are more likely to be newly dispensed a benzodiazepine following a recent, acute-care hospital admission.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 01:09:04