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Titolo:
Early diagnosis of central nervous system aspergillosis with combination use of cerebral diffusion-weighted echo-planar magnetic resonance image and polymerase chain reaction of cerebrospinal fluid
Autore:
Kami, M; Shirouzu, I; Mitani, K; Ogawa, S; Matsumura, T; Kanda, Y; Masumoto, T; Saito, T; Tanaka, Y; Maki, K; Honda, H; Chiba, S; Ohtomo, K; Hirai, H; Yazaki, Y;
Indirizzi:
Univ Tokyo, Dept Hematol & Oncol, Bunkyo Ku, Tokyo 1138655, Japan Univ Tokyo Tokyo Japan 1138655 & Oncol, Bunkyo Ku, Tokyo 1138655, Japan
Titolo Testata:
INTERNAL MEDICINE
fascicolo: 1, volume: 38, anno: 1999,
pagine: 45 - 48
SICI:
0918-2918(199901)38:1<45:EDOCNS>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
MENINGITIS; DISEASE; DNA;
Keywords:
polymerase chain reaction of the cerebrospinal fluid (CSF-PCR); diffusion-weighted echo-planar magnetic resonance imaging (DWI); cerebral infarction; invasive aspergillosis; acute lymphoblastic leukemia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Hirai, H Univpankyo, Dept Hematol & Oncol, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Ja Univ Tokyo 7-3-1 Hongo Tokyo Japan 1138655 go, Tokyo 1138655, Ja
Citazione:
M. Kami et al., "Early diagnosis of central nervous system aspergillosis with combination use of cerebral diffusion-weighted echo-planar magnetic resonance image and polymerase chain reaction of cerebrospinal fluid", INTERN MED, 38(1), 1999, pp. 45-48

Abstract

We treated a patient diagnosed as central nervous system (CNS) aspergillosis with the combined use of cerebral diffusion-weighted echo-planar magnetic resonance imaging (DWI) and polymerase chain reaction of the cerebrospinal fluid (CSF-PCR), DWI, a cutting-edge imaging modality to reveal the earliest changes of cerebral infarction, detected cerebral fungal embolization when the conventional computed tomographic scan and magnetic resonance imaging failed to reveal it. CSF-PCR demonstrated the presence of Aspergillus-specific DNA in the specimen, when the conventional examination and culture of CSF were nonspecific or negative. These diagnostic methods could be useful in the early diagnosis of CNS aspergillosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 13:26:51