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Titolo:
IgG index in acute idiopathic peripheral facial palsy
Autore:
Inci, IO; Gedizlioglu, M; Mavioglu, H; Uzuncan, N;
Indirizzi:
Izmir Social Secur Hosp, Dept Neurol, Izmir, Turkey Izmir Social Secur Hosp Izmir Turkey r Hosp, Dept Neurol, Izmir, Turkey
Titolo Testata:
ACTA NEUROLOGICA SCANDINAVICA
fascicolo: 2, volume: 99, anno: 1999,
pagine: 117 - 120
SICI:
0001-6314(199902)99:2<117:IIIAIP>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
BELLS-PALSY; CEREBROSPINAL-FLUID; NEUROLOGICAL DISORDERS; DISEASE; VIRUS; SERUM; PRINCIPLES; ALBUMIN; CSF;
Keywords:
peripheral facial palsy; Bell's palsy; IgG index;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Gedizlioglu, M 1785 Sok 13-9 Bostanli, TR-35540 Izmir, Turkey 1785 Sok 13-9 Bostanli Izmir Turkey TR-35540 zmir, Turkey
Citazione:
I.O. Inci et al., "IgG index in acute idiopathic peripheral facial palsy", ACT NEUR SC, 99(2), 1999, pp. 117-120

Abstract

Objectives - Etiologic hypotheses in acute idiopathic peripheral facial palsy (AIPFP) mostly point to an immunologic dysfunction, probably virus-induced. Though various immunologic abnormalities are reported, the problem is still unsolved. We investigated intrathecal immunoglobulin synthesis in AIPFP as a clue for central nervous system (CNS) immunopathology. Material andmethods - We studied IgG index in 24 patients with AIPFP, 10 with other neurological diseases (OND) and 17 with multiple sclerosis (MS). CSF and serum IgG were measured by radial immunodiffusion technique. IgG index is calculated according to Tibbling's formula. Results - IgG indexes were abnormal in 6 patients with AIPFP, 3 with OND and 10 with MS patients. There was no statistical difference between AIPFP and OND groups, while marked difference existed between AIPFP and MS groups. Conclusion - Though IgG indexes werehigh in 25% of AIPFP patients, statistical analyses did not show any significance of this finding. Lack of a positive result might reflect non-existence of an extensive immunologic pathology within CNS, excluding a very limited one.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 09:05:21