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Titolo:
Theory of the BOLD effect in the capillary region: An analytical approach for the determination of T-2* in the capillary network of myocardium
Autore:
Bauer, WR; Nadler, W; Bock, M; Schad, LR; Wacker, C; Hartlep, A; Ertl, G;
Indirizzi:
Univ Mannheim, Med Klin, Mannheim, Germany Univ Mannheim Mannheim Germany iv Mannheim, Med Klin, Mannheim, Germany KFA Julich GmbH, Forschungszentrum, HLRZ, Julich, Germany KFA Julich GmbHJulich Germany Forschungszentrum, HLRZ, Julich, Germany German Canc Res Ctr, Dept Biophys, D-6900 Heidelberg, Germany German Canc Res Ctr Heidelberg Germany D-6900 D-6900 Heidelberg, Germany
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 1, volume: 41, anno: 1999,
pagine: 51 - 62
SICI:
0740-3194(199901)41:1<51:TOTBEI>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
OXYGENATION DEPENDENCE; TRANSVERSE RELAXATION; CONTRAST; BLOOD; PROTONS; TISSUES; FIELDS; HEART; T-1;
Keywords:
BOLD effect; capillary; myocardium; transverse relaxation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Bauer, WR Univ167idelberg, Klinikum Mannheim, Med Klin, Theodor Kutzer Ufer 1-3, D-68 Univ Heidelberg Theodor Kutzer Ufer 1-3 Mannheim Germany D-68167
Citazione:
W.R. Bauer et al., "Theory of the BOLD effect in the capillary region: An analytical approach for the determination of T-2* in the capillary network of myocardium", MAGN RES M, 41(1), 1999, pp. 51-62

Abstract

This article presents an analytical approach for the quantification of theblood oxygen level dependent (BOLD) effect in the capillary region. The capillary geometry of myocardium is considered. The relaxation rate R-2* is determined as a function of the capillary radius R-c, the intracapillary volume fraction REV, and the diffusion coefficient D, When the intracapillary volume fraction is small, the approximation R-2* - RBV . tau(-1) . (root 1 (tau delta omega)(2) - 1) is valid, with the correlation time tau = (R-c(2)/4D) . (\In RBV\/(1 - RBV)). The predictions of this model agree well with numerical simulations and experimental data of others and with data recently measured by our group. Magn Reson Med 41:51-62, 1999. (C) 1999 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 10:48:36