Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Interactions between cyclodextrins and Tm-III chelates of polyazamacrocycles as studied by NMR in aqueous solution
Autore:
Zitha-Bovens, E; van Bekkum, H; Peters, JA; Geraldes, CFGC;
Indirizzi:
Delftdsniv Technol, Organ Chem & Catalysis Lab, NL-2628 BL Delft, Netherlan Delft Univ Technol Delft Netherlands NL-2628 BL 2628 BL Delft, Netherlan Univ Coimbra, Dept Biochem, P-3000 Coimbra, Portugal Univ Coimbra Coimbra Portugal P-3000 t Biochem, P-3000 Coimbra, Portugal Univ Coimbra, Ctr Neurosci, P-3000 Coimbra, Portugal Univ Coimbra Coimbra Portugal P-3000 Neurosci, P-3000 Coimbra, Portugal
Titolo Testata:
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
fascicolo: 2, , anno: 1999,
pagine: 287 - 293
SICI:
1434-1948(199902):2<287:IBCATC>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
NUCLEAR-MAGNETIC-RESONANCE; WATER PROTON RELAXATION; LANTHANIDE COMPLEXES; INCLUSION COMPLEXES; BETA-CYCLODEXTRIN; MOLECULAR-STRUCTURE; GAMMA-CYCLODEXTRIN; ALPHA-CYCLODEXTRIN; IONS; SPECTROSCOPY;
Keywords:
MRI contrast agents; macrocyclic ligands; cyclodextrins; host-guest chemistry; lanthanides;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
47
Recensione:
Indirizzi per estratti:
Indirizzo: Peters, JA Delft Univ Technol, Organ Chem & Catalysis Lab, Julianalaan 136, NL-2628 BL Delft Univ Technol Julianalaan 136 Delft Netherlands NL-2628 BL
Citazione:
E. Zitha-Bovens et al., "Interactions between cyclodextrins and Tm-III chelates of polyazamacrocycles as studied by NMR in aqueous solution", EUR J INORG, (2), 1999, pp. 287-293

Abstract

The interactions between a-, b-, and g-CD and the Tm-III chelates of the macrocyclic polyaminopolycarboxylates DOTA and NOTA were studied with the use of H-1- and C-13-NMR shift and relaxation rate measurements. Interactionswere only observed between Tm(DOTA)(-) and g-CD. The structure and the stability of the concerning supramolecular structures was elucidated by fitting of the NMR titration curves to a theoretical model. It appears that an inclusion compound is formed, where the hydrophobic macrocyclic part of the chelate sits in the g-CD cavity. This inclusion compound binds a second Tm(DOTA)(-) molecule at the outside lower rim of the CD cone. The binding occurs probably via hydrogen bonds between non-chelated carboxylate oxygen atomsof the concerning Tm(DOTA)(-) and CH2OH groups of the g-CD molecule, whichare in a favorable position due to opening of the g-CD cone angle as a result of the inclusion of the first g-CD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 19:17:02