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Titolo:
Synthesis of an imidazo[1,2-e]purine-acridine heterodimer for targeting abasic sites in DNA
Autore:
Belmont, P; Alarcon, K; Demeunynck, M; Lhomme, J;
Indirizzi:
Univ Grenoble 1, CNRS, UMR 5616, LEDSS, F-38041 Grenoble 9, France Univ Grenoble 1 Grenoble France 9 616, LEDSS, F-38041 Grenoble 9, France
Titolo Testata:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
fascicolo: 2, volume: 9, anno: 1999,
pagine: 233 - 236
SICI:
0960-894X(19990118)9:2<233:SOAIHF>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
REPAIR; MOLECULES; DUPLEX;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Demeunynck, M Univ Grenoble 1, CNRS, UMR 5616, LEDSS, BP 53, F-38041 Grenoble 9, France Univ Grenoble 1 BP 53 Grenoble France 9 Grenoble 9, France
Citazione:
P. Belmont et al., "Synthesis of an imidazo[1,2-e]purine-acridine heterodimer for targeting abasic sites in DNA", BIOORG MED, 9(2), 1999, pp. 233-236

Abstract

Cyclization of 8-bromo-9-alkylaminoethyl-adenine quantitatively affords a substituted imidazo[1,2-e]purine. The corresponding heterodimer, imidazo[1,2-e]purine-acridine, was prepared and its interaction with abasic site containing oligonucleotides was studied. (C) 1999 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 05:23:40