Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Substituted heterocyclic analogs as selective COX-2 inhibitors in the Flosulide class
Autore:
Ouimet, N; Chan, CC; Charleson, S; Claveau, D; Gordon, R; Guay, D; Li, CS; Ouellet, M; Percival, DM; Riendeau, D; Wong, E; Zamboni, R; Prasit, P;
Indirizzi:
MerckH9Rosst Canada Inc, Merck Frosst Ctr Therapeut Res, Pointe Claire, PQMerck Frosst Canada Inc Pointe Claire PQ Canada H9R 4P8 Pointe Claire, PQ
Titolo Testata:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
fascicolo: 2, volume: 9, anno: 1999,
pagine: 151 - 156
SICI:
0960-894X(19990118)9:2<151:SHAASC>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
NONSTEROIDAL ANTIINFLAMMATORY DRUGS; CYCLOOXYGENASE-2 INHIBITORS; INDUCIBLE CYCLOOXYGENASE; DERIVATIVES; CONVERSION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Ouimet, N Mercklaire,t Canada Inc, Merck Frosst Ctr Therapeut Res, POB 1005, Pointe C Merck Frosst Canada Inc POB 1005 Pointe Claire PQ Canada H9R 4P8
Citazione:
N. Ouimet et al., "Substituted heterocyclic analogs as selective COX-2 inhibitors in the Flosulide class", BIOORG MED, 9(2), 1999, pp. 151-156

Abstract

Substituted heterocyclic analogs in the Flosulide class were investigated as potential selective . 6-(4-Ethyl-2-thiazolylthio)-5-methanesulfonamido-3H-isobenzofuran-1-one 14 was found to be the optimal compound in the serieswith superior in vitro and in vivo activities. (C) 1999 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 05:44:43