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Titolo:
Latent inhibition in smokers vs. nonsmokers: Interaction with number or intensity of preexposures?
Autore:
Della Casa, V; Hofer, I; Feldon, J;
Indirizzi:
Swissch,d Inst Technol, Lab Behav Biol & Funct Toxicol, CH-8603 Schwerzenba Swiss Fed Inst Technol Schwerzenbach Switzerland CH-8603 603 Schwerzenba
Titolo Testata:
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
fascicolo: 2, volume: 62, anno: 1999,
pagine: 353 - 359
SICI:
0091-3057(199902)62:2<353:LIISVN>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC AMPHETAMINE; DOPAMINE RELEASE; HEALTHY PEOPLE; NICOTINE; HALOPERIDOL; STIMULUS; RAT; DURATION; SCHIZOPHRENIA; DISRUPTION;
Keywords:
latent inhibition; attention; smoking; nicotine; human;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Feldon, J Swiss603d Inst Technol, Lab Behav Biol & Funct Toxicol, Schorenstr 16, CH-8 Swiss Fed Inst Technol Schorenstr 16 Schwerzenbach SwitzerlandCH-8603
Citazione:
V. Della Casa et al., "Latent inhibition in smokers vs. nonsmokers: Interaction with number or intensity of preexposures?", PHARM BIO B, 62(2), 1999, pp. 353-359

Abstract

Latent inhibition (LI) refers to the slowing of learning about a stimulus after preexposure, i.e., previous presentation of the stimulus without any consequence. This report summarizes results of four studies investigating the effect of being a smoker or nonsmoker on auditory LI as a function of procedural parameters, namely number (10 vs. 30) and intensity (low vs. high)of preexposed stimuli. In general, the number of preexposures did not affect LI, whereas low-intensity stimuli led to greater LI than high-intensity stimuli. These findings underline the importance of automatic vs, controlled processing of the preexposed stimuli for the development of human LI. Smokers showed increased LI compared to nonsmokers in low-intensity task versions as well as compared to both smokers and nonsmokers in high-intensity versions. These findings may indicate that nicotinic effects on LI depend on the robustness of LI in the control group. (C) 1999 Elsevier Science Inc.

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Documento generato il 05/04/20 alle ore 00:16:17