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Titolo:
Interaction between paired-pulse facilitation and long-term potentiation in the projection from hippocampal area CA1 to the subiculum
Autore:
Commins, S; Gigg, J; Anderson, M; OMara, SM;
Indirizzi:
Univ Dublin Trinity Coll, Dept Psychol, Dublin 2, Ireland Univ Dublin Trinity Coll Dublin Ireland 2 ept Psychol, Dublin 2, Ireland
Titolo Testata:
NEUROREPORT
fascicolo: 18, volume: 9, anno: 1998,
pagine: 4109 - 4113
SICI:
0959-4965(199812)9:18<4109:IBPFAL>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYNAPTIC TRANSMISSION; DENTATE GYRUS; RAT; PLASTICITY; SLICES;
Keywords:
hippocampus; long-term potentiation; paired-pulse facilitation; subiculum; time-dependency;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: O'Mara, SM Univ Dublin Trinity Coll, Dept Psychol, Dublin 2, Ireland Univ Dublin Trinity Coll Dublin Ireland 2 , Dublin 2, Ireland
Citazione:
S. Commins et al., "Interaction between paired-pulse facilitation and long-term potentiation in the projection from hippocampal area CA1 to the subiculum", NEUROREPORT, 9(18), 1998, pp. 4109-4113

Abstract

STUDIES of the interaction between long-term potentiation (LTP) and paired-pulse facilitation (PPF) may throw light on the role of presynaptic factors in LTP. We examine here, for the first time, the nature of PPF in the CA1-subiculum projection. PPF peaks at a 50 ms interstimulus interval (ISI) and is evident at ISIs from 10 to 500 ms. There is no PPF effect at a 1000 msISI. PPF decreases in magnitude post-LTP induction across the middle rangeof ISI values tested (30, 50 and 100 ms). There is a positive correlation between initial PPF values and LTP; this correlation increases as the ISI increases. Initial values and the change in PPF post-LTP are also negativelycorrelated. (C) 1998 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 07:32:17