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Titolo:
Bone healing of tibial lengthening is delayed by cigarette smoking: Study of bone mineral density and torsional strength on rabbits
Autore:
Ueng, SWN; Lin, SS; Wang, CR; Liu, SJ; Tai, CL; Shih, CH;
Indirizzi:
Chang Gung Mem Hosp, Dept Orthopaed Surg, Keelung 204, Taiwan Chang Gung Mem Hosp Keelung Taiwan 204 thopaed Surg, Keelung 204, Taiwan Chang Gung Univ, Dept Engn Mech, Keelung, Taiwan Chang Gung Univ KeelungTaiwan ng Univ, Dept Engn Mech, Keelung, Taiwan
Titolo Testata:
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
fascicolo: 1, volume: 46, anno: 1999,
pagine: 110 - 115
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-FLOW; DISTRACTION; NICOTINE; INHALATION; NONUNION; SMOKERS;
Keywords:
cigarette smoking; tibial lengthening; bone healing; bone mineral density; torsional strength;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Ueng, SWN Changwanng Mem Hosp, Dept Orthopaed Surg, 222 Mai Chin Rd, Keelung 204, Tai Chang Gung Mem Hosp 222 Mai Chin Rd Keelung Taiwan 204 204, Tai
Citazione:
S.W.N. Ueng et al., "Bone healing of tibial lengthening is delayed by cigarette smoking: Study of bone mineral density and torsional strength on rabbits", J TRAUMA, 46(1), 1999, pp. 110-115

Abstract

Objective: We investigated the effect intermittent cigarette smoke inhalation on the bone healing of tibial. lengthening in rabbits. Methods: Twelve male rabbits were divided into two groups of sh animals each. The first group underwent intermittent cigarette smoke inhalation, and the second group did not undergo intermittent cigarette smoke inhalation. Each animal's right tibia was lengthened 5 mm by using an uniplanar lengthening device. Bane mineral density (BMD) study was performed for all of the animals 1 day before operation and 3, 4, 5, and 6 weeks after operation. Allof the animals were killed 6 weeks postoperatively for biomechanical testing. Results: By using the preoperative BMD as an internal control, we found that the BMD of the smoke-inhalation group was decreased significantly compared with the non-smoke-inhalation group. The mean %BMD at 3, 4, 5, and 6 weeks were 49.9%, 61.2%, 65.9%, and 71.0%, respectively, in the smoke-inhalation group, whereas the mean %BMD were 54.9%, 71.8%, 76.4%, and 82.0%, respectively, in the non-smoke-inhalation group (two-tailed t test, p > 0.05, p <0.01, p < 0.01 and p < 0.01 at 3, 4, 5, and 6 weeks, respectively). By using the contralateral nonoperated tibia as internal control, we found that torsional strength of the smoke-inhalation group was decreased significantlycompared with the non-smoke-inhalation group. The mean percentage of maximal torque was 63.8% in the smoke-inhalation group, whereas the mean percentage of maximal torque was 77.1% in the non-smoke-inhalation group (two tailed t test, p < 0.01). Conclusion: This study suggests that cigarette smoking delays the mineralization during the bone heating process of distraction osteogenesis and, thus, decreases the mechanical strength of the regenerating bone.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 07:01:56