Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Intraepithelial and invasive squamous cell carcinoma of the conjunctiva: analysis of 60 cases
Autore:
Tunc, M; Char, DH; Crawford, B; Miller, T;
Indirizzi:
CPMC Davies, Tumori Fdn, San Francisco, CA 94114 USA CPMC Davies San Francisco CA USA 94114 i Fdn, San Francisco, CA 94114 USA Univ Calif San Francisco, Dept Ophthalmol, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA UnivACalif San Francisco, Francis I Proctor Fdn, San Francisco, CA 94143 US Univ Calif San Francisco San Francisco CA USA 94143 rancisco, CA 94143 US
Titolo Testata:
BRITISH JOURNAL OF OPHTHALMOLOGY
fascicolo: 1, volume: 83, anno: 1999,
pagine: 98 - 103
SICI:
0007-1161(199901)83:1<98:IAISCC>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMMUNODEFICIENCY-VIRUS INFECTION; SURFACE EPITHELIAL DYSPLASIA; TOPICAL MITOMYCIN-C; ULTRAVIOLET-RADIATION; SKIN-CANCER; NEOPLASIA; CORNEAL; TUMORS; RISK; 5-FLUOROURACIL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
57
Recensione:
Indirizzi per estratti:
Indirizzo: Char, DH CPMCADavies, Tumori Fdn, Suite 309,45 Castro St, San Francisco, CA 94114 US CPMC Davies Suite 309,45 Castro St San Francisco CA USA 94114 US
Citazione:
M. Tunc et al., "Intraepithelial and invasive squamous cell carcinoma of the conjunctiva: analysis of 60 cases", BR J OPHTH, 83(1), 1999, pp. 98-103

Abstract

Aim-To evaluate the clinical features, treatment results, and recurrence rates in patients with either intraepithelial or invasive squamous cell carcinoma of the conjunctiva. Methods-Retrospective analysis of 60 cases (22 conjunctival intraepithelial and 38 invasive squamous cell carcinomas) to determine patterns of clinical presentation, aetiological factors, and treatment results. The mean patient age was 64 years old. 70% of the patients were male. Patients were treated with a variety of therapies, depending on the degree of tumour involvement; most cases were treated with frozen section controlled excision and adjunctive cryotherapy. Modified eye wall resection or enucleation was done for intraocular invasion and exenteration was done for orbital involvement. Results-Red eye (68%) and ocular irritation (57%) were the most common presenting symptoms. 44% of the patients had other eye findings consistent with extensive solar exposure. 20% of the patients had a history of malignant skin tumours. Visceral malignancies developed in 8%. Scleral involvement was present in 14 (37%), intraocular involvement in five (13%), and orbital invasion in four (11%) cases with invasive squamous cell carcinoma. After a mean follow up of 56 months (18-226 months) the rate of new or recurrent tumours was 4.5% for intraepithelial squamous carcinoma and 5.3% for invasivesquamous cell carcinoma. No patient developed metastases or tumour relateddeaths. Conclusion-Excision with intraoperative control of the surgical margins and adjunctive cryotherapy results in good tumour control rates.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 07:00:25