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Titolo:
A high-affinity hemoglobin is expressed in the notochord of amphioxus, Branchiostoma californiense
Autore:
Bishop, JJ; Vandergon, TL; Green, DB; Doeller, JE; Kraus, DW;
Indirizzi:
Pepperdine Univ, Div Nat Sci, Malibu, CA 90263 USA Pepperdine Univ MalibuCA USA 90263 iv, Div Nat Sci, Malibu, CA 90263 USA Univ Alabama, Dept Biol, Birmingham, AL 35294 USA Univ Alabama BirminghamAL USA 35294 Dept Biol, Birmingham, AL 35294 USA
Titolo Testata:
BIOLOGICAL BULLETIN
fascicolo: 3, volume: 195, anno: 1998,
pagine: 255 - 259
SICI:
0006-3185(199812)195:3<255:AHHIEI>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
CYTOPLASMIC HEMOGLOBIN; SEQUENCES; EVOLUTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Vandergon, TL Pepperdine Univ, Div Nat Sci, 24255 Pacific Coast Highway, Malibu, CA 90263 Pepperdine Univ 24255 Pacific Coast Highway Malibu CA USA 90263
Citazione:
J.J. Bishop et al., "A high-affinity hemoglobin is expressed in the notochord of amphioxus, Branchiostoma californiense", BIOL B, 195(3), 1998, pp. 255-259

Abstract

In the phylum Chordata, only members of the subphylum Vertebrata were thought to express hemoglobin (Hb). Here we document the existence of intracellular Hb expressed;in members of the subphylum Cephalochordata. Hemoglobin is expressed in myotome tissue and in notochord cells within the body of amphioxus. Both notochord and myotome tissue Hbs have a molecular size consistent with a dimeric molecule made up of two non-covalently linked monomers each of approximately 19 kD. The notochord Hb has a relatively high oxygen-binding affinity, with an apparent P-50 Of 0.036 kPa (0.27 mm Hg), and it does not bind oxygen cooperatively. The notochord Hb may be involved in facilitating oxygen delivery and providing a short-term oxygen store within the notochord cells in order to maintain a high level of aerobic metabolism in support of the sustained contraction necessary for notochord function.

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Documento generato il 27/11/20 alle ore 02:17:12