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Titolo:
Smoking withdrawal, nicotine dependence and prepulse inhibition of the acoustic startle reflex
Autore:
Kumari, V; Gray, JA;
Indirizzi:
Univonondon, Inst Psychiat, Dept Psychol, Sect Cognit Psychopharmacol, Lond Univ London London England SE5 8AF ol, Sect Cognit Psychopharmacol, Lond
Titolo Testata:
PSYCHOPHARMACOLOGY
fascicolo: 1, volume: 141, anno: 1999,
pagine: 11 - 15
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANIMAL-MODEL; SCHIZOPHRENIC-PATIENTS; CIGARETTE-SMOKING; HABITUATION; DISRUPTION; DISORDER; RATS; STIMULATION; HALOPERIDOL; CLOZAPINE;
Keywords:
prepulse inhibition; acoustic startle reflex; smelting withdrawal; nicotine dependence;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Kumari, V Univrespigny Inst Psychiat, Dept Psychol, Sect Cognit Psychopharmacol, De C Univ London De Crespigny Pk London England SE5 8AF rmacol, De C
Citazione:
V. Kumari e J.A. Gray, "Smoking withdrawal, nicotine dependence and prepulse inhibition of the acoustic startle reflex", PSYCHOPHAR, 141(1), 1999, pp. 11-15

Abstract

The present study examined the relationship between nicotine dependence asmeasured by the Fagerstrom Tolerance Questionnaire (FTQ) and prepulse inhibition (PPI) of the acoustic startle reflex measured after overnight smoking withdrawal in a non-clinical population of male smokers with no history of psychiatric disorders or drug/alcohol abuse. It was found that smokers who scored high (>median) on the FTQ showed significantly less PPI as compared to those scoring low (<median) on this scale. This finding further supports a role for nicotine in modulation of PPI, as has previously been found in rats and also in human beings.

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Documento generato il 23/01/20 alle ore 18:15:31