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Titolo:
Co-localization of interleukin-1 receptor type I and interleukin-1 receptor antagonist with vasopressin in magnocellular neurons of the paraventricular and supraoptic nuclei of the rat hypothalamus
Autore:
Diana, A; van Dam, AM; Winblad, B; Schultzberg, M;
Indirizzi:
HuddingeeriatrHosp, Karolinska Inst, Dept Clin Neurosci & Family Med, Div G Huddinge Univ Hosp Huddinge Sweden S-14186 Neurosci & Family Med, Div G Free Univ Amsterdam, Fac Med, Dept Pharmacol, Neurosci Res Inst, NL-1081 BT Free Univ Amsterdam Amsterdam Netherlands NL-1081 BT es Inst, NL-1081 BT
Titolo Testata:
NEUROSCIENCE
fascicolo: 1, volume: 89, anno: 1999,
pagine: 137 - 147
SICI:
0306-4522(199903)89:1<137:COIRTI>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORTICOTROPIN-RELEASING-FACTOR; MESSENGER-RNA; IL-1 RECEPTOR; ARGININE-VASOPRESSIN; SICKNESS BEHAVIOR; GENE-EXPRESSION; MEDIAN-EMINENCE; BLOOD-PRESSURE; MOUSE-BRAIN; PITUITARY;
Keywords:
co-existence; corticotropin-releasing factor; cytokine; immunohistochemistry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
58
Recensione:
Indirizzi per estratti:
Indirizzo: Schultzberg, M HuddingeeriatrHosp, Karolinska Inst, Dept Clin Neurosci & Family Med, Div G Huddinge Univ Hosp Huddinge Sweden S-14186 ily Med, Div G
Citazione:
A. Diana et al., "Co-localization of interleukin-1 receptor type I and interleukin-1 receptor antagonist with vasopressin in magnocellular neurons of the paraventricular and supraoptic nuclei of the rat hypothalamus", NEUROSCIENC, 89(1), 1999, pp. 137-147

Abstract

Interleukin-1 receptor type I and interleukin-l receptor antagonist were found in magnocellular neurons of the paraventricular and supraoptic nuclei of the rat hypothalamus by immunohistochemical detection. Double-labelling experiments revealed that both proteins occurred in vasopressin-containing neurons. A similar distribution pattern was observed in a group of vasopressin-positive accessory magnocellular neurons. Axons emanating from the interleukin-l receptor type I- and interleukin-l receptor antagonist-immunoreactive neuronal cell bodies could be seen within the hypothalamic nuclei, andvaricosities expressing interleukin-l receptor antagonist immunoreactivitywere observed in the internal zone of the median eminence, as well as in the hypothalamo-pituitary projection. The co-localization of interleukin-l receptor type I with vasopressin is in agreement with findings that interleukin-l has a stimulatory effect on vasopressin synthesis and release. The hypothalamic neurons may serve as a source of interleukin-l receptor antagonist to balance the effects of interleukin-1. (C) 1998 IBRO. Published by Elsevier Science Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 06:33:58