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Titolo:
Vaginal estrogen creams: Use patterns among a cohort of women
Autore:
Keenan, NL; Franks, AL; Croft, JB; Scholes, D; Murray, ET;
Indirizzi:
Ctrreventontrol & Prevent, Div Adult & Community Hlth, Natl Ctr Chron Dis P Ctr Dis Control & Prevent Atlanta GA USA 30341 Hlth, Natl Ctr Chron Dis P Grp Hlth Cooperat Puget Sound, Ctr Hlth Studies, Seattle, WA 98101 USA GrpHlth Cooperat Puget Sound Seattle WA USA 98101 Seattle, WA 98101 USA
Titolo Testata:
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
fascicolo: 1, volume: 47, anno: 1999,
pagine: 65 - 70
SICI:
0002-8614(199901)47:1<65:VECUPA>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
HORMONE REPLACEMENT THERAPY; POST-MENOPAUSAL WOMEN; UROGENITAL ATROPHY; ELDERLY WOMEN; RISK-FACTORS; OLDER WOMEN; DISEASE; 17-BETA-ESTRADIOL; HEALTH;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Keenan, NL Ctrreventontrol41 Prevent, Div Adult & Community Hlth, Natl CtrChron Dis P Ctr Dis Control & Prevent 4770 Buford Highway NE,Mailstop K-45Atlanta GA USA 30341
Citazione:
N.L. Keenan et al., "Vaginal estrogen creams: Use patterns among a cohort of women", J AM GER SO, 47(1), 1999, pp. 65-70

Abstract

OBJECTIVE: To assess the prevalence, amount, and duration of use of vaginal estrogen cream among several birth cohorts of women from 1983 through 1992. DESIGN: Analyses are based on automated membership, pharmacy, and hospitaldischarge databases from Group Health Cooperative (GHC) of Puget Sound, a large health maintenance organization in Seattle, Washington. PARTICIPANTS: A total of 33,822 women, aged 45 years and older as of December 31, 1983, who were enrolled in GHC from 1983 to 1992 or who were enrolled at baseline and died in the following decade. RESULTS: About 24% of the cohort had filled at least one prescription for vaginal estrogen cream during 1983 through 1992, and about 60% of the usershad more than one prescription filled. The annual birth cohort-specific prevalence of having filled one or more prescriptions for vaginal estrogen creams ranged between 1.6 and 8.2% across birth cohorts, whereas the average annual prevalence for the cohort was between 5.3 and 6.8%. The total amount, duration of use, and proportion of total estrogen exposure from creams increased with age of the birth cohort. Among the 733 women with intact uteriwho were long-term cream users, 60.4% had no progestin prescriptions whileaveraging 22.1 tubes of estrogen cream. CONCLUSION: The prescription-filling patterns for estrogen in this cohort show an increase in the amount, years of use, and proportion of estrogen exposure from creams with the age of the birth cohort and extensive unopposedcream use among a small proportion of women with intact uteri. The systemic effects of vaginal estrogen cream among older postmenopausal women with urogenital atrophy deserve closer scrutiny.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 07:38:43