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Titolo:
Morphologic aspects of fibromyalgia
Autore:
Pongratz, DE; Spath, M;
Indirizzi:
Univ Munich, Klinikum Innenstadt, Med Klin, D-80336 Munich, Germany Univ Munich Munich Germany D-80336 dt, Med Klin, D-80336 Munich, Germany Univ Munich, Klinikum Innenstadt, Neurol Klin, D-80336 Munich, Germany Univ Munich Munich Germany D-80336 Neurol Klin, D-80336 Munich, Germany
Titolo Testata:
ZEITSCHRIFT FUR RHEUMATOLOGIE
, volume: 57, anno: 1998, supplemento:, 2
pagine: 47 - 51
SICI:
0340-1855(1998)57:<47:MAOF>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
MUSCLE;
Keywords:
fibromyalgia; type II fiber atrophy; lipid and mitochondria accumulation; ragged red fiber; mitochondrial genoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Pongratz, DE UnivGermany, Klinikum Innenstadt, Med Klin, Ziemssenstr 1, D-80336 Munich, Univ Munich Ziemssenstr 1 Munich Germany D-80336 336 Munich,
Citazione:
D.E. Pongratz e M. Spath, "Morphologic aspects of fibromyalgia", Z RHEUMATOL, 57, 1998, pp. 47-51

Abstract

The most common morphological finding in muscle biopsis in longstanding fibromyalgia is type II fiber atrophy. This can be found in many other conditions such as disuse atrophy, affections of the corticospinal tracts, steroid atrophy, and other different neuromuscular disorders. An increase in lipid droplets and a slight proliferation of mitochondria in type I muscle fibers are correlated with the duration of fibromyalgia. In some cases we couldfind some ragged red fibers (RRF) which histochemically show a pronounced accumulation of lipids and mitochondria and single fiber defects of cytochrome-c-oxidase. In some fibromyalgia patients with RRF, we could find deletions of the mitochondrial genoma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 04:28:12