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Titolo:
Evaluation of combining upper respiratory tract swab samples with cerebrospinal fluid examination for the diagnosis of enteroviral meningitis in children
Autore:
Foray, S; Pailloud, F; Thouvenot, D; Floret, D; Aymard, M; Lina, B;
Indirizzi:
Ctrancel Reference Enterovirus & Hepatite A, Virol Lab, F-69373 Lyon 08, Fr Ctr Natl Reference Enterovirus & Hepatite A Lyon France 08 3 Lyon 08, Fr Hop Edouard Herriot, Serv Urgences Pediat, Lyon, France Hop Edouard Herriot Lyon France iot, Serv Urgences Pediat, Lyon, France
Titolo Testata:
JOURNAL OF MEDICAL VIROLOGY
fascicolo: 2, volume: 57, anno: 1999,
pagine: 193 - 197
SICI:
0146-6615(199902)57:2<193:EOCURT>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
POLYMERASE CHAIN-REACTION; CENTRAL-NERVOUS-SYSTEM; ASEPTIC-MENINGITIS; SENSITIVE DETECTION; INFECTIONS; MANAGEMENT; SPECIMENS; DISEASE; INFANTS; RNA;
Keywords:
aseptic meningitis; enterovirus; cerebrospinal fluid; pharyngeal swabs; polymerase chain reaction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Lina, B Ctr,Natl Reference Enterovirus & Hepatite A, Virol Lab, Domaine Rockefeller Ctr Natl Reference Enterovirus & Hepatite A Domaine Rockefeller Lyon France 08
Citazione:
S. Foray et al., "Evaluation of combining upper respiratory tract swab samples with cerebrospinal fluid examination for the diagnosis of enteroviral meningitis in children", J MED VIROL, 57(2), 1999, pp. 193-197

Abstract

In a prospective comparative study, the use of combined analysis of upper respiratory tract swab samples and cerebrospinal fluid (CSF) samples was assessed to improve the detection rate of enteroviral meningitis in children. An enterovirus was detected in 32% of patients with aseptic meningitis when testing CSF samples alone compared with 71.5% when combining CSF and respiratory tract findings. An enterovirus was detected in 17% of respiratory tract samples in an age- and sex-matched control group without meningitis. Thus, combining the examination of upper respiratory tract with CSF findingsmay improve the detection rate of enteroviral meningitis. Upper respiratory tract samples should be included in the diagnosis scheme to differentiatebenign enteroviral meningitis from other life-threatening infections of the central nervous system. (C) 1999 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 07:12:36