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Titolo:
MS205 minisatellite diversity in Basques: Evidence for a pre-neolithic component
Autore:
Alonso, S; Armour, JAL;
Indirizzi:
Univ Nottingham, Queens Med Ctr, Div Genet, Nottingham NG7 2UH, England Univ Nottingham Nottingham England NG7 2UH , Nottingham NG7 2UH, England
Titolo Testata:
GENOME RESEARCH
fascicolo: 12, volume: 8, anno: 1998,
pagine: 1289 - 1298
SICI:
1054-9803(199812)8:12<1289:MMDIBE>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
MITOCHONDRIAL GENE POOL; MICROSATELLITE LOCI; MODERN HUMANS; ALLELE SIZE; POPULATION; ORIGIN; POLYMORPHISMS; CONSTRAINTS; LINEAGES; EUROPE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
53
Recensione:
Indirizzi per estratti:
Indirizzo: Alonso, S Univ Nottingham, Queens Med Ctr, Div Genet, Nottingham NG7 2UH, England Univ Nottingham Nottingham England NG7 2UH am NG7 2UH, England
Citazione:
S. Alonso e J.A.L. Armour, "MS205 minisatellite diversity in Basques: Evidence for a pre-neolithic component", GENOME RES, 8(12), 1998, pp. 1289-1298

Abstract

A number of studies have suggested that Basques might be a relic of Mesolithic Europeans who escaped much of the homogenization brought about by the Neolithic expansion. In an attempt to add new insights into this hypothesis, MS205 minisatellite diversity has been investigated by Minisatellite Variant Repeat (MVR) analysis in a sample of >100 autochthonous individuals From the Basque Country, along with 24 Castilian (N. Spain) and 23 individualsFrom the United Kingdom. These populations were examined in the context ofthe available world database for MS205 alleles. To deduce the similaritiesamong populations, we have applied a phylogenetic approach that takes intoaccount similarity between alleles. The variability of these populations seems to be a subset of the greater and presumably older African diversity, as has been suggested previously for non-Africans. Within non-Africans, Basques seem to cluster with other Northern European populations; however, some apparently Basque-specific alleles can be dated back to post-Aurignacian times, supporting the continuity of some lineages of this population since the Upper Paleolithic period.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/10/20 alle ore 01:29:17