Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Material and functional properties of articular cartilage and patellofemoral contact mechanics in an experimental model of osteoarthritis
Autore:
Herzog, W; Diet, S; Suter, E; Mayzus, P; Leonard, TR; Muller, C; Wu, JZ; Epstein, M;
Indirizzi:
Univadalgary, Fac Kinesiol, Human Performance Lab, Calgary, AB T2N 1N4, Can Univ Calgary Calgary AB Canada T2N 1N4 ance Lab, Calgary, AB T2N 1N4, Can Inst Francais Mecan Avancee, Clermont Ferrand, France Inst Francais Mecan Avancee Clermont Ferrand France ont Ferrand, France
Titolo Testata:
JOURNAL OF BIOMECHANICS
fascicolo: 12, volume: 31, anno: 1998,
pagine: 1137 - 1145
SICI:
0021-9290(199812)31:12<1137:MAFPOA>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTERIOR CRUCIATE LIGAMENT; DIFFERENT LENGTHS; SKELETAL-MUSCLE; TRANSECTION; BONE; IMMOBILIZATION; HYPERTROPHY; LAYERS;
Keywords:
cartilage; contact mechanics; osteoarthritis; anterior cruciate ligament; cat; biomechanics; knee; ligament transection;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Herzog, W Univ,Calgary, Fac Kinesiol, Human Performance Lab, 2500 Univ Dr NW, Calgary Univ Calgary 2500 Univ Dr NW Calgary AB Canada T2N 1N4 , Calgary
Citazione:
W. Herzog et al., "Material and functional properties of articular cartilage and patellofemoral contact mechanics in an experimental model of osteoarthritis", J BIOMECHAN, 31(12), 1998, pp. 1137-1145

Abstract

The purposes of this study were to determine the in situ functional and material properties of articular cartilage in an experimental model of joint injury, and to quantify the corresponding in situ joint contact mechanics. Experiments were performed in the anterior cruciate ligament (ACL) transected knee of the cat and the corresponding, intact contralateral knee, 16 weeks following intervention. Cartilage thickness, stiffness, effective Young's modulus, and permeability were measured and derived from six locations ofthe knee. The total contact area and peak pressures in the patellofemoral joint were obtained in situ using Fuji Pressensor film, and comparisons between experimental and contralateral joint were made for corresponding loading conditions. Total joint contact area and peak pressure were increased and decreased significantly (alpha = 0.01), respectively, in the experimentalcompared to the contralateral joint. Articular cartilage thickness and stiffness were increased and decreased significantly (alpha = 0.01), respectively, in the experimental compared to the contralateral joint in the four femoral and patellar test locations. Articular cartilage material properties (effective Young's modulus and permeability) were the same in the ACL-transected and intact joints. These results demonstrate for the first time the effect of changes in articular cartilage properties on the load transmissionacross a joint. They further demonstrate a substantial change in the jointcontact mechanics within 16 weeks of ACL transection. The results were corroborated by theoretical analysis of the contact mechanics in the intact and ACL-transected knee using biphasic contact analysis and direct input of cartilage properties and joint surface geometry from the experimental animals. We conclude that the joint contact mechanics in the ACL-transected cat change within 16 weeks of experimental intervention. (C) 1998 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 13:34:03