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Titolo:
Mood disturbances in motor neurone disease
Autore:
Moore, MJ; Moore, PB; Shaw, PJ;
Indirizzi:
Newcastleear, Hosp, Dept Social Work, Newcastle Upon Tyne NE4 6BE, Tyne & W Newcastle Gen Hosp Newcastle Upon Tyne Tyne & Wear England NE4 6BE ne & W S Tyneside Dist Hosp, Dept Psychiat, S Shields NE34 0PL, England S Tyneside Dist Hosp S Shields England NE34 0PL hields NE34 0PL, England Royalr,ictoria Infirm, Dept Neurol, Newcastle Upon Tyne NE7 4LP, Tyne & Wea Royal Victoria Infirm Newcastle Upon Tyne Tyne & Wear England NE7 4LP Wea
Titolo Testata:
JOURNAL OF THE NEUROLOGICAL SCIENCES
, volume: 160, anno: 1998, supplemento:, 1
pagine: S53 - S56
SICI:
0022-510X(199810)160:<S53:MDIMND>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEPRESSION;
Keywords:
MND (motor neurone disease); ALS (amyotrophic lateral sclerosis); depression; anxiety; life events; personality;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Moore, MJ Newcastle6BE, Hosp, Dept Social Work, Westgate Rd, Newcastle Upon Tyne NE4 Newcastle Gen Hosp Westgate Rd Newcastle Upon Tyne Tyne & Wear England NE4 6BE
Citazione:
M.J. Moore et al., "Mood disturbances in motor neurone disease", J NEUR SCI, 160, 1998, pp. S53-S56

Abstract

This study explores the severity of depression and anxiety experienced by patients suffering from motor neurone disease and seeks to link this to illness progression, recent life events and personality factors. The 18 patients who participated in the study were assessed for the presence of psychiatric symptoms using the Beck Depressive Inventory and the Hospital Anxiety and Depression Scale. The severity of the illness and the life events duringthe course of the illness were measured using the Norris scale and the Holmes and Rahe Social Readjustment Rating Scale. A personality assessment wasmade using the Eysenck Personality Questionnaire (EPQ). Only four out of these 18 patients (23%) in the study suffered depression and of these three (17%) were mild and one (6%) was of moderate severity. A further six patients (33%) were rated as borderline depression. Only two patients suffered from an anxiety state and both had concurrent mild depression. No correlations of depression were found with the life events or illness progression. Only the L sub-scale of the EPQ (15.6+/-4.9) exceeds values expected for the general population. Despite the severity and frequency of life events duringthe course of the illness, most patients do not develop a depressive illness. The reason for this unexpected result is unclear. Depression is believed to result from underactivity of the serotonergic neurotransmitter system. However, in MND this system is relatively unaffected in contrast to dementia and other neurodegenerative disorders. The patients' high L scores suggest that many may cope with their illness by widespread use of denial as a psychological defence. (C) 1998 Published by Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 02:45:43