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Titolo:
Descriptive information of topographic parameters computed at the optic nerve head with the Heidelberg Retina Tomograph
Autore:
Saruhan, A; Orgul, S; Kocak, I; Prunte, C; Flammer, J;
Indirizzi:
Univ Basel, Eye Clin, CH-4012 Basel, Switzerland Univ Basel Basel Switzerland CH-4012 ye Clin, CH-4012 Basel, Switzerland
Titolo Testata:
JOURNAL OF GLAUCOMA
fascicolo: 6, volume: 7, anno: 1998,
pagine: 420 - 429
SICI:
1057-0829(199812)7:6<420:DIOTPC>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
OPEN-ANGLE GLAUCOMA; LASER-SCANNING TOMOGRAPHY; NEURORETINAL RIM AREA; VISUAL-FIELD DEFECT; INTRAOCULAR-PRESSURE; OCULAR HYPERTENSION; STRUCTURAL DAMAGE; TOPOMETRIC DATA; NORMAL EYES; DISC SHAPE;
Keywords:
confocal scanning laser ophthalmoscopy; glaucoma; optic nerve head;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
70
Recensione:
Indirizzi per estratti:
Indirizzo: Orgul, S Univ Basel, Eye Clin, POB, CH-4012 Basel, Switzerland Univ Basel POB Basel Switzerland CH-4012 4012 Basel, Switzerland
Citazione:
A. Saruhan et al., "Descriptive information of topographic parameters computed at the optic nerve head with the Heidelberg Retina Tomograph", J GLAUCOMA, 7(6), 1998, pp. 420-429

Abstract

Purpose: To analyze the frequency distribution and descriptive informationof topometric data obtained with the Heidelberg Retina Tomograph (HRT) in a normal population. Methods: Topographic measurements of the optic disc were acquired and evaluated using the HRT in 225 subjects between 12 and 90 years of age. After randomly selecting one eye per subject, the frequency distributions, mean values, minima, maxima, and first, fifth, fiftieth, ninety-fifth, and ninety-ninth percentiles were evaluated for topographic parameters computed by theHRT. The influence of age, intraocular pressure (IOP), disc size, and discshape on optic disc topometric data was analyzed. A principal component analysis of the topometric parameters was performed. The frequency distributions, mean values, minima, maxima, and first, fifth, fiftieth, ninety-fifth,and ninety-ninth percentiles of the interocular difference in topographic parameters were evaluated. Results: All topographic parameters showed a unimodal but not necessarily normal distribution. None of the parameters showed a relevant correlation with age, IOP (in the normal range), and overall shape of the anterior opticnerve, but a few parameters showed a clinically significant correlation with disc size. A principal component analysis identified four relevant factors (optic nerve cup, retinal nerve fiber layer, optic disc size, and optic nerve cup shape) in the entire data set of optic nerve topometric data. Theabsolute value of all interocular differences in topographic parameters showed an asymmetric but unimodal distribution. Conclusion: The mathematical description of the optic nerve cup shape provides information on optic nerve head topography independently from cupping,nerve fiber layer thickness, and disc size. potentially, quantification offurther aspects in optic nerve head topography might improve the discriminatory power of computerized quantitative optic nerve head analysis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 12:13:38