Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Promoting activity of the herbicide dicamba (2-methoxy-3,6-dichlorobenzoicacid) in two stage hepatocarcinogenesis
Autore:
Espandiari, P; Glauert, HP; Lee, EY; Robertson, LW;
Indirizzi:
Univ Kentucky, Grad Ctr Toxicol, Lexington, KY 40536 USA Univ Kentucky Lexington KY USA 40536 Ctr Toxicol, Lexington, KY 40536 USA Univ Kentucky, Dept Nutr & Food Sci, Lexington, KY 40536 USA Univ Kentucky Lexington KY USA 40536 & Food Sci, Lexington, KY 40536 USA Univ Kentucky, Dept Pathol, Lexington, KY 40536 USA Univ Kentucky Lexington KY USA 40536 Dept Pathol, Lexington, KY 40536 USA
Titolo Testata:
INTERNATIONAL JOURNAL OF ONCOLOGY
fascicolo: 1, volume: 14, anno: 1999,
pagine: 79 - 84
SICI:
1019-6439(199901)14:1<79:PAOTHD>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
HYPOLIPIDEMIC PEROXISOME PROLIFERATORS; ALTERED HEPATIC FOCI; RAT-LIVER; PERFLUORODECANOIC ACID; QUANTITATIVE STEREOLOGY; WY-14,643; DIETHYLNITROSAMINE; CARCINOGENESIS; PLASTICIZERS; ENHANCEMENT;
Keywords:
dicamba; altered hepatic foci; promotion; peroxisome proliferator;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Robertson, LW Univ Kentucky, Grad Ctr Toxicol, 306 Hlth Sci Res Bldg, Lexington, KY 40536 Univ Kentucky 306 Hlth Sci Res Bldg Lexington KY USA 40536 6
Citazione:
P. Espandiari et al., "Promoting activity of the herbicide dicamba (2-methoxy-3,6-dichlorobenzoicacid) in two stage hepatocarcinogenesis", INT J ONCOL, 14(1), 1999, pp. 79-84

Abstract

Our goal was to examine whether dicamba, a widely-used broad leaf herbicide, has promoting activity in two-stage hepatocarcinogenesis. Female SpragueDawley rats were given a single dose of diethylnitrosamine and then diets containing dicamba, or phenobarbital, or both for six months. The number and volume of placental glutathione-S-transferase-positive, glucose-6-phosphatase-negative or ATPase-negative foci were quantified in the liver. Dicambaalone did not increase the number or volume of these altered hepatic foci. Dicamba did, however, show a significant effect on the number or volume ofcertain markers in animals also treated with phenobarbital. These data show that dicamba in combination with other promoters may have weak promoting activity in two-stage hepatocarcinogenesis in the rat.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 15:45:39