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Titolo:
Four-eyelid sebaceous cell carcinoma following irradiation
Autore:
Rumelt, S; Hogan, NR; Rubin, PAD; Jakobiec, FA;
Indirizzi:
Harvardcoliv, Massachusetts Eye & Ear Infirm, Sch Med, Ophthalm Pathol & On Harvard Univ Boston MA USA 02114 ar Infirm, Sch Med, Ophthalm Pathol & On HarvardPlast, Massachusetts Eye & Ear Infirm, Sch Med, Dept Ophthalmol,EyeHarvard Univ Boston MA USA 02114 Ear Infirm, Sch Med, Dept Ophthalmol,Eye HarvardtUniv, Massachusetts Eye & Ear Infirm, Sch Med, Dept Ophthalmol,Orbi Harvard Univ Boston MA USA 02114 ar Infirm, Sch Med, Dept Ophthalmol,Orbi
Titolo Testata:
ARCHIVES OF OPHTHALMOLOGY
fascicolo: 12, volume: 116, anno: 1998,
pagine: 1670 - 1672
SICI:
0003-9950(199812)116:12<1670:FSCCFI>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
OCULAR ADNEXA; GLAND;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Jakobiec, FA Harvardcoliv, Massachusetts Eye & Ear Infirm, Sch Med, Ophthalm Pathol & On Harvard Univ 243 Charles St Boston MA USA 02114 m Pathol & On
Citazione:
S. Rumelt et al., "Four-eyelid sebaceous cell carcinoma following irradiation", ARCH OPHTH, 116(12), 1998, pp. 1670-1672

Abstract

Background: Sebaceous cell carcinoma is a distinctive tumor of the eyelid associated with a high rate of metastasis and mortality. Involvement of both upper and lower lids has been described; however, involvement of all 4 eyelids is extremely rare. Objective: To describe the evaluation and diagnosis of the clinicopathologic features in a 74-year-old patient with 4-eyelid sebaceous carcinoma and a history of whole face irradiation for eczema. Methods: Bilateral eyelid, conjunctiva, map, and fine needle biopsy of enlarged, submandibular lymph node specimens were stained with hematoxylin-eosin and oil-red-O for light microscopy and fresh-frozen sections were evaluated by electron microscopy. Results: The biopsy specimens from the eyelids and conjunctiva showed sebaceous carcinoma cells in the meibomian glands and scattered within the conjunctival epithelium. The cells were moderately well differentiated. Similarcells stained with oil-red-O were found in the submandibular lymph nodes. Conclusions: The appearance of bilateral sebaceous carcinoma supports the concept of simultaneous occurrence of multiple primaries in specific patients, especially after radiation therapy. Patients with a history of facial irradiation and atypical eyelid lesions should be evaluated for malignant tumors such as sebaceous carcinoma.

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Documento generato il 18/09/20 alle ore 16:52:25