Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The anaerobic degradation of L-serine and L-threonine in enterobacteria: networks of pathways and regulatory signals
Autore:
Sawers, G;
Indirizzi:
John Innes Ctr Plant Sci Res, Nitrogen Fixat Lab, Norwich NR4 7UH, Norfolk, John Innes Ctr Plant Sci Res Norwich Norfolk England NR4 7UH UH, Norfolk,
Titolo Testata:
ARCHIVES OF MICROBIOLOGY
fascicolo: 1, volume: 171, anno: 1998,
pagine: 1 - 5
SICI:
0302-8933(199812)171:1<1:TADOLA>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
ESCHERICHIA-COLI K-12; INTEGRATION HOST FACTOR; TDC OPERON; PEPTOSTREPTOCOCCUS-ASACCHAROLYTICUS; GENE; EXPRESSION; DEHYDRATASES; PROTEIN; IDENTIFICATION; INVOLVEMENT;
Keywords:
L-serine; L-threonine; anaerobiosis; pyridoxal 5 '-phosphate enzymes; iron-sulfur enzymes; glycyl radical enzymes; metabolism;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Sawers, G John Innes Ctr Plant Sci Res, Nitrogen Fixat Lab, Norwich NR4 7UH, Norfolk, John Innes Ctr Plant Sci Res Norwich Norfolk England NR4 7UH k,
Citazione:
G. Sawers, "The anaerobic degradation of L-serine and L-threonine in enterobacteria: networks of pathways and regulatory signals", ARCH MICROB, 171(1), 1998, pp. 1-5

Abstract

The mechanisms controlling the biosynthesis and degradation of L-serine and L-threonine are remarkably complex. Their metabolism forms a network of path ways linking several amino acids, central primary metabolites such as pyruvate, oxaloacetate and 3-phosphoglycerate, and C-1 metabolism. Studies on the degradation of these amino acids in Escherichia coli have revealed the involvement of fascinating enzymes that utilise quite diverse catalytic mechanisms. Moreover, it is emerging that both environmental and metabolic signals have a major impact in controlling enzyme synthesis. This is exemplified by the anaerobically regulated tdc operon, which encodes a metabolic pathway for the degradation of serine and threonine. Studies on this pathwayare beginning to provide insights into how an organism adapts its genetic makeup to meet the physiological demands of the cell.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 06:55:37