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Titolo:
Contributions of nuclear medicine to the diagnosis of recurrent cerebral tumors and cerebral radionecrosis
Autore:
Bader, JB; Samnick, S; Schaefer, A; Hagen, T; Moringlane, JR; Feiden, W; Piepgras, U; Kirsch, CM;
Indirizzi:
Univ Saarlandes, Radiol Klin, Abt Nukl Med, D-66421 Homburg, Germany Univ Saarlandes Homburg Germany D-66421 kl Med, D-66421 Homburg, Germany Univ Saarlandes, Neurochirurg Klin, Homburg, Germany Univ Saarlandes Homburg Germany es, Neurochirurg Klin, Homburg, Germany Univ Saarlandes, Inst Neuropathol, Homburg, Germany Univ Saarlandes Homburg Germany des, Inst Neuropathol, Homburg, Germany
Titolo Testata:
RADIOLOGE
fascicolo: 11, volume: 38, anno: 1998,
pagine: 924 - 929
SICI:
0033-832X(199811)38:11<924:CONMTT>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
GER
Soggetto:
POSITRON EMISSION TOMOGRAPHY; ALPHA-METHYL-TYROSINE; F-18 FLUORODEOXYGLUCOSE; BRAIN-TUMORS; L-3-IODO-ALPHA-METHYL TYROSINE; RADIATION NECROSIS; GLIOMAS; PET; SPECT; ONCOLOGY;
Keywords:
cerebral tumors; recurrence; FDG-PET; IMT-SPECT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Bader, JB Univ,Saarlandes, Radiol Klin, Abt Nukl Med, Oskar Orth Str, D-66421 Homburg Univ Saarlandes Oskar Orth Str Homburg Germany D-66421 Homburg
Citazione:
J.B. Bader et al., "Contributions of nuclear medicine to the diagnosis of recurrent cerebral tumors and cerebral radionecrosis", RADIOLOGE, 38(11), 1998, pp. 924-929

Abstract

The evaluation of brain tumor recurrence and therapy-induced benign changes following surgery and/or irradiation is a diagnostic challenge for imaging methods based on either morphology (cCT/MRI) or function (SPECT/PET). Current literature and the present data of our own patients demonstrate the diagnostic efficiency of IMT-SPECT and FDG-PET in the detection of recurrenceand in-vivo grading. Thirty-nine patients suspected of brain tumor recurrence at follow-up were studied by FDG-PET and IMT-SPECT. Thirty-four of 39 patients showed recurrences; in 12 cases even a change in the grade of malignancy was observed. All high-grade recurrences could be confirmed by eithermethods. IMT-SPECT showed a higher sensitivity in detecting low-grade tumors at recurrence. In contrast to IMT-SPECT, FDG-PET supports sufficient in-vivo grading. Both methods can be used to differentiate between tumor recurrence and radionecrosis. In conclusion the results of our study demonstratethe efficiency of IMT-SPECT and FDG-PET in confirming recurrences and determining the actual tumor grade.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/21 alle ore 07:05:29