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Titolo:
Nitric oxide synthase in the auditory brain stem
Autore:
Reuss, S;
Indirizzi:
Univ Mainz, Sch Med, Dept Anat, D-55099 Mainz, Germany Univ Mainz Mainz Germany D-55099 Med, Dept Anat, D-55099 Mainz, Germany
Titolo Testata:
NEUROREPORT
fascicolo: 16, volume: 9, anno: 1998,
pagine: 3643 - 3646
SICI:
0959-4965(19981116)9:16<3643:NOSITA>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
SUPRACHIASMATIC NUCLEUS; MAMMALIAN COCHLEA; NADPH-DIAPHORASE; RAT; NEURONS;
Keywords:
auditory brain stem; hamster; NADPH-diaphorase; neuronal nitric oxide synthase; rat; superior olivary complex;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Reuss, S Univ Mainz, Sch Med, Dept Anat, D-55099 Mainz, Germany Univ Mainz Mainz Germany D-55099 t Anat, D-55099 Mainz, Germany
Citazione:
S. Reuss, "Nitric oxide synthase in the auditory brain stem", NEUROREPORT, 9(16), 1998, pp. 3643-3646

Abstract

THE auditory superior olivary complex (SOC), a group of inter-related brain stem nuclei, sends efferents to a variety of neuronal structures including the cochlea and the inferior colliculus. The present study conducted in rats and hamsters sought to investigate whether the neuroactive substance nitric oxide (NO) is produced in the rodent SOC. Immunohisto- and cytochemistry of the NO-synthesizing enzyme neuronal NO-synthase (nNOS), and histochemistry (NADPH-diaphorase activity of nNOS) was used. Perikarya stained by either method were found in the medial nucleus of the trapezoid body and in periolivary nuclei projecting to the cochlea, while terminals were observed mainly in the lateral superior olivary nucleus and in the superior paraolivary nucleus. These data demonstrate the existence of nNOS in the rodent SOCand provide evidence that nitric oxide acts as neuroactive substance in the auditory brain stem and the organ of Corti. NeuroReport 9: 3643-3646 (C) 1998 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 00:40:22