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Titolo:
Synthesis, chemistry and conformational properties of piperazic acids
Autore:
Ciufolini, MA; Xi, N;
Indirizzi:
Univ Lyon 1, Lab Synth & Methodol Organ, F-69622 Villeurbanne, France UnivLyon 1 Villeurbanne France F-69622 an, F-69622 Villeurbanne, France Ecole Super Chim Phys & Elect Lyon, F-69622 Villeurbanne, France Ecole Super Chim Phys & Elect Lyon Villeurbanne France F-69622 e, France
Titolo Testata:
CHEMICAL SOCIETY REVIEWS
fascicolo: 6, volume: 27, anno: 1998,
pagine: 437 - 445
SICI:
0306-0012(199811)27:6<437:SCACPO>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
UNUSUAL AMINO-ACID; ELECTROPHILIC AMINATION; ALPHA-AMINO; (3S)-2,3,4,5-TETRAHYDROPYRIDAZINE-3-CARBOXYLIC ACID; (3S)-PIPERAZIC ACIDS; ANTRIMYCIN-DV; DERIVATIVES; DESIGN; LUZOPEPTINS; BBM-928-A;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
45
Recensione:
Indirizzi per estratti:
Indirizzo: Ciufolini, MA Univlleurbanne,b Synth & Methodol Organ, 43 Bd 11 Novembre 1918, F-69622 Vi Univ Lyon 1 43 Bd 11 Novembre 1918 Villeurbanne France F-69622
Citazione:
M.A. Ciufolini e N. Xi, "Synthesis, chemistry and conformational properties of piperazic acids", CHEM SOC RE, 27(6), 1998, pp. 437-445

Abstract

We review methods for the preparation of piperazic acids ("piz") and significant aspects of their chemistry. Special attention is devoted to issues relating to acylation of these non-proteinogenic amino acids, given the importance of these operations for the synthesis of piz-containing oligopeptides. We also provide an account of the unique conformational properties of piperazic acids and discuss their behavior as rigid proline equivalents that should be quite useful for the creation and study of peptide turn mimics.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 22:07:45