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Titolo:
Cortical areas with enhanced activation during object-centred spatial information processing - A PET study
Autore:
Honda, M; Wise, SP; Weeks, RA; Deiber, MP; Hallett, M;
Indirizzi:
NINDS, Human Motor Control Sect, Med Neurol Branch, NIH, Bethesda, MD 20892 NINDS Bethesda MD USA 20892 t, Med Neurol Branch, NIH, Bethesda, MD 20892 NIMH, Lab Syst Neurosci, NIH, Poolesville, MD USA NIMH Poolesville MD USA IMH, Lab Syst Neurosci, NIH, Poolesville, MD USA
Titolo Testata:
BRAIN
, volume: 121, anno: 1998,
parte:, 11
pagine: 2145 - 2158
SICI:
0006-8950(199811)121:<2145:CAWEAD>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSTERIOR PARIETAL CORTEX; POSITRON EMISSION TOMOGRAPHY; LATERAL INTRAPARIETAL AREA; HUMAN EXTRASTRIATE CORTEX; FUNCTIONAL-ANATOMY; VISUAL PATHWAYS; MACAQUE MONKEYS; GRASP REPRESENTATIONS; PRIMATE PREMOTOR; FRONTAL-CORTEX;
Keywords:
cerebral blood flow; object-centred coordinate; screen-centred coordinate; occipitotemporal cortex; frontoparietal network;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
69
Recensione:
Indirizzi per estratti:
Indirizzo: Hallett, M NINDS,,10man Motor Control Sect, Med Neurol Branch, NIH, Bldg 10,Room 5N226 NINDS Bldg 10,Room 5N226,10 Ctr Dr,MSC-1428 Bethesda MD USA 20892
Citazione:
M. Honda et al., "Cortical areas with enhanced activation during object-centred spatial information processing - A PET study", BRAIN, 121, 1998, pp. 2145-2158

Abstract

The phenomenon of object-centred unilateral neglect suggests that some neural networks process spatial information relative to reference objects. To examine object-centred information processing, we measured regional cerebral blood flow in 11 normal subjects with PET. During each PET scan, a subject viewed a sample stimulus followed by a cue on a video screen, The sample consisted of two polygons, termed 'objects', each located in a corner of the screen. A small target spot appeared in a corner of each polygon, There were two tasks: the visuomotor task and the matching-to-sample task, In the visuomotor task, the subject moved a joystick in a direction indicated by either the location of the target spot inside the object (if object-centred coordinates were operative) or the location of the object relative to the video screen (if screen-centred coordinates were operative;), In the matching-to-sample task, the subject moved the joystick to report whether the relevant spatial information (object- or screen-centred) in the cue matched thesample. In both the visuomotor and the matching-to-sample task, use of object-centred (versus screen- or viewer-centred) information caused augmentedactivation in the inferior occipitotemporal cortex, bilaterally, in the left superior occipital gyrus, and in both the thalamus and the brainstem, Inaddition, in the visuomotor task such activation occurred in the right posterior parietal cortex and in the left ventral premotor, dorsolateral prefrontal and anterior supplementary motor areas. These findings suggest the involvement of the occipitotemporal cortex and a broad frontoparietal networkwhen, as in the visuomotor task, object-centred information guides movement, When the same data underlie declarative reports, as in the matching-to-sample task, thp occipitotemporal cortex remains engaged but frontoparietal network diminishes in importance.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 23:37:51