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Titolo:
Improvement with disodium cromoglycate of neutrophil phagocytosis and respiratory burst activity in a patient with hyperimmunoglobulin E syndrome
Autore:
Kojima, K; Inoue, Y; Katayama, Y; Kataoka, M; Sunami, K; Fukuda, S; Sezaki, T; Omoto, E; Harada, M;
Indirizzi:
Natl Okayama Hosp, Dept Med, Okayama, Japan Natl Okayama Hosp Okayama Japan Okayama Hosp, Dept Med, Okayama, Japan Okayama Univ, Sch Med, Dept Med 2, Okayama 700, Japan Okayama Univ Okayama Japan 700 , Sch Med, Dept Med 2, Okayama 700, Japan
Titolo Testata:
ALLERGY
fascicolo: 11, volume: 53, anno: 1998,
pagine: 1101 - 1103
SICI:
0105-4538(199811)53:11<1101:IWDCON>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
HYPER-IGE SYNDROME; GAMMA PRODUCTION; CELLS; AIDS;
Keywords:
disodium cromoglycate; hyperimmunoglobulin E syndrome; immunodeficiency; neutrophil deficiency;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Kojima, K Ehime024,fectural Cent Hosp, Dept Med, 83 Kasuga Cho, Matsuyama,Ehime 7900 Ehime Prefectural Cent Hosp 83 Kasuga Cho Matsuyama Ehime Japan7900024
Citazione:
K. Kojima et al., "Improvement with disodium cromoglycate of neutrophil phagocytosis and respiratory burst activity in a patient with hyperimmunoglobulin E syndrome", ALLERGY, 53(11), 1998, pp. 1101-1103

Abstract

We report a case of hyperimmunoglobulin E syndrome (HIE) complicated by neutrophil deficiency which was successfully treated with oral administrationof disodium cromoglycate. A 48-year-old Japanese man with HIE developed Streptococcus pnenmoniae meningitis. Laboratory tests after the meningitis revealed persistent neutropenia (300-800/mm(3)) and defects of phagocytosis and bacterial killing by neutrophils. Administration of disodium cromoglycate was started, and neutrophil counts gradually increased to 1200-1600/mm(3). The impaired neutrophil activities returned to normal. The patient improved clinically; during the 2-year treatment, he had only two brief episodes of the common cold. Disodium cromoglycate may have potential clinical use in the treatment of cases of HIE even with neutrophil deficiency.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 18:20:12