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Titolo:
BIOCHEMICAL MODIFICATIONS IN THE BLOOD AND THE HEATED FLUIDS DURING INTRAPERITONEAL CHEMOHYPERTHERMIA
Autore:
BERNY C; MANCHON M; PANTEIX G; GILLY FN; SAYAG A; MIALON A; LE KE; BALTASSAT P; CARRY PY; BRAILLON G;
Indirizzi:
CTR HOSP LYON SUD,DEPT BIOCHEM 3A F-69310 PIERRE BENITE FRANCE CTR HOSP LYON SUD,DEPT SURG F-69310 PIERRE BENITE FRANCE CTR HOSP LYON SUD,DEPT ANAESTHESIA & INTENS CARE F-69310 PIERRE BENITE FRANCE
Titolo Testata:
Oncology
fascicolo: 5, volume: 50, anno: 1993,
pagine: 362 - 365
SICI:
0030-2414(1993)50:5<362:BMITBA>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
HYPERTHERMIC PERFUSION; PERITONEAL RECURRENCE; GASTRIC-CANCER; SURGERY;
Keywords:
BIOCHEMICAL MODIFICATION; HYPERTHERMIA; INTRAPERITONEAL PERFUSION; TUMOR CELL LYSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
5
Recensione:
Indirizzi per estratti:
Citazione:
C. Berny et al., "BIOCHEMICAL MODIFICATIONS IN THE BLOOD AND THE HEATED FLUIDS DURING INTRAPERITONEAL CHEMOHYPERTHERMIA", Oncology, 50(5), 1993, pp. 362-365

Abstract

The biochemical changes in blood during intraperitoneal chemohyperthermia (IPCH) were examined by carrying out complete assessments before and after the operation. These assessments were made up of 23 parameters: Na, K, Cl, CO2, urea, creatinine, proteins, glucose, calcium, phosphates, magnesium, bilirubin, uric acid, lactic acid, CRP, ASAT, ALAT,CK, LDH, gamma-GT, ALP, lipase, and amylase. Only 5 of these parameters showed significant changes: proteins, urea, ALP, gamma-GT, lactic acid. The protein and urea levels decreased due to hemodilution inducedby the perfusion of fluids. ALP and gamma-GT levels decreased, possibly due to localized inhibition of secretion. Lactic acid levels increased due to the movement of lactates from the heated fluid into the blood. The study of biochemical changes within the heated fluids was madeusing the following parameters: CA 125, CA 19-9, CEA, ASAT, ALAT, CK,LDH, gamma-GT, ALP, lipase, uric acid, phosphates, proteins, Na, K, Cl, urea, creatinine, and magnesium. Between the beginning and the end of IPCH, significant increases were found in the levels of CA 125 (+173%), proteins (+190%), ASAT (+130%), LDH (+103%), K+ (+232%), PO4 (+134%), and uric acid (+99%). These increases indicate the existence of asignificant degree of cellular lysis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 05:54:48