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Titolo:
AGE-RELATED TRENDS IN CARDIOVASCULAR MORBIDITY AND PHYSICAL FUNCTIONING IN THE ELDERLY - THE CARDIOVASCULAR HEALTH STUDY
Autore:
BILD DE; FITZPATRICK A; FRIED LP; WONG ND; HAAN MN; LYLES M; BOVILL E; POLAK JF; SCHULZ R;
Indirizzi:
NHLBI,DECA,7550 WISCONSIN AVE,FED BLDG,ROOM 300 BETHESDA MD 20892 UNIV WASHINGTON,DEPT BIOSTAT SEATTLE WA 98195 JOHNS HOPKINS UNIV,DEPT MED BALTIMORE MD 21218 UNIV CALIF IRVINE,PREVENT CARDIOL PROGRAM IRVINE CA 92717 UNIV CALIF DAVIS,DEPT COMMUNITY & INT HLTH DAVIS CA 95616 WAKE FOREST UNIV,BOWMAN GRAY SCH MED,DEPT INTERNAL MED WINSTON SALEM NC 27103 UNIV VERMONT,DEPT PATHOL BURLINGTON VT 05405 BRIGHAM & WOMENS HOSP,DEPT RADIOL BOSTON MA 02115 UNIV PITTSBURGH,DEPT PSYCHIAT PITTSBURGH PA 15260 UNIV PITTSBURGH,UNIV CTR SOCIAL & URBAN RES PITTSBURGH PA 15260
Titolo Testata:
Journal of the American Geriatrics Society
fascicolo: 10, volume: 41, anno: 1993,
pagine: 1047 - 1056
SICI:
0002-8614(1993)41:10<1047:ATICMA>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
VENTRICULAR EJECTION FRACTION; CORONARY-ARTERY DISEASE; LIFE EXPECTANCY; VITAL CAPACITY; HEART-DISEASE; POPULATION; INFARCTION; DISABILITY; ISSUES; IMPACT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social Sciences Citation Index
Science Citation Index Expanded
Citazioni:
32
Recensione:
Indirizzi per estratti:
Citazione:
D.E. Bild et al., "AGE-RELATED TRENDS IN CARDIOVASCULAR MORBIDITY AND PHYSICAL FUNCTIONING IN THE ELDERLY - THE CARDIOVASCULAR HEALTH STUDY", Journal of the American Geriatrics Society, 41(10), 1993, pp. 1047-1056

Abstract

Objective: To describe relationships between age and subclinical cardiovascular disease, manifest chronic disease, and physical functioningand limitations among persons aged 65 years and older, with emphasis on the ''oldest old,'' those 85 years and older. Design: Observationalpopulation-based study Setting: Four U.S. communities: Forsyth County, North Carolina; Sacramento County, California; Washington County, Maryland; and Pittsburgh, Pennsylvania. Participants: 5,201 men and women aged 65 years and older. Measurements: Demographic data; histories of cardiovascular disease (CVD), chronic lung disease, arthritis, diabetes, and hypertension; measures of subclinical disease including arm and ankle blood pressures, internal carotid wall thickness and stenosis, ejection fraction, left ventricular mass, fractional shortening, anddiastolic function, electrocardiographic left ventricular hypertrophyand cardiac injury score, forced expiratory flow and volume; functional status including self-reported physical functioning, hearing and sight limitations and health status, and performance-based measures of function. These variables were examined among men and women in three age groups: 65-74 years, 75-84 years, and 85+ years. Subgroups of participants with and without manifest CVD were also examined. Main Results:In women, the prevalence of CVD and other chronic conditions increased with age, and the highest rates occurred among those 85 years and older. In men, prevalence rateS increased between the two younger groups, but the oldest group had lower than expected rates for coronary heart disease, cerebrovascular disease, hypertension, and chronic lung disease. In contrast, there were strong age-related linear trends in mostof the subclinical measures of blood pressure atherosclerosis and pulmonary function and in virtually all measures of functional status in both gender groups across the age range. There was a particularly marked decline in functional status between the two older age groups. While subclinical disease was greater and functional status was poorer among those with manifest CVD, with few exceptions, age-related trends were not significantly different between the two groups. Conclusions: Lower than expected prevalence rates of CVD among those aged 85 years and older, particularly among men, in this study of community-dwelling elderly may represent selection bias or a real plateauing in disease prevalence with age. However, subclinical disease appears to increase and functional status to decline across the age range in both men and women regardless of the presence of CVD. The apparent increase in subclinical disease with age indicates potential for CVD prevention after age 65.

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Documento generato il 27/11/20 alle ore 02:13:22