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Titolo:
RESERPINE RECONSIDERED - NO ASSOCIATION WITH SERIOUS PEPTIC-ULCER DISEASE
Autore:
SHORR RI; RAY WA; DAUGHERTY JR; GRIFFIN MR;
Indirizzi:
VANDERBILT UNIV,MED CTR,SCH MED,DEPT PREVENT MED,DIV PHARMACOEPIDEMIOL NASHVILLE TN 37232
Titolo Testata:
Journal of general internal medicine
fascicolo: 9, volume: 8, anno: 1993,
pagine: 510 - 512
SICI:
0884-8734(1993)8:9<510:RR-NAW>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Keywords:
RESERPINE; PEPTIC ULCER DISEASE; RISK ASSESSMENT;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
R.I. Shorr et al., "RESERPINE RECONSIDERED - NO ASSOCIATION WITH SERIOUS PEPTIC-ULCER DISEASE", Journal of general internal medicine, 8(9), 1993, pp. 510-512

Abstract

A history of peptic ulcer disease is frequently cited as a contraindication to the use of reserpine. However, the risk of ulcer disease associated with the use of reserpine at current therapeutic doses is unknown. To address this question, the authors conducted a nested case-control study of the association between reserpine use and hospitalizations for peptic ulcer disease in elderly Tennessee Medicaid enrollees. When compared with that of nonusers of reserpine, the relative risk of hospitalization for peptic ulcer disease was 0.8 (95% CI, 0.6-1.0) among current users and 0.8 (95% CI, 0.5-1.3) among former users. The authors' data provide evidence that reserpine is not associated with ulcer disease in elderly persons and suggest that a history of ulcer disease need not be a contraindication to the use of this drug.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 10:34:10