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Titolo:
12-0-TETRADECANOYLPHORBOL 13-ACETATE (TPA)-INDUCED ENZYMATIC CHANGE OF HUMAN NON-T, NON-B LYMPHOID LEUKEMIA-CELL LINES
Autore:
SASAKI R; KUBONISHI I; MINOWADA J; BOLLUM FJ; MIURA Y; TAKAKU F;
Indirizzi:
JICHI MED SCH,DEPT INTERNAL MED 1 MINAMI KAWACHI TOCHIGI 32904 JAPAN
Titolo Testata:
Haematologia
fascicolo: 2, volume: 25, anno: 1993,
pagine: 111 - 121
SICI:
0017-6559(1993)25:2<111:11(ECO>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Keywords:
PEANUT AGGLUTININ (PNA); POLY(A) POLYMERASE; SIALYTRANSFERASE (S-T); TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE (TDT); 12-0-TETRADECANOYLPHORBOL-13-ACETATE (TPA);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
R. Sasaki et al., "12-0-TETRADECANOYLPHORBOL 13-ACETATE (TPA)-INDUCED ENZYMATIC CHANGE OF HUMAN NON-T, NON-B LYMPHOID LEUKEMIA-CELL LINES", Haematologia, 25(2), 1993, pp. 111-121

Abstract

Culture of two lymphoid leukemia cell lines with 5 x 10(-9) to 10(-7)M 12-0-tetradecanoyl-phorbol 13-acetate (TPA) induced the significantincrease in sialyltransferase, acid phosphatase and butyrate esteraseactivities, the decrease in poly(A) polymerase and terminal deoxynucleotidyl transferase (TdT) activities. B4-, J5-, TdT- or PNA-positive cells were decreased in TPA-treated cells, while B1-positive cells wereincreased. These results suggest enzymatic changes as an aspect of TPA-induced differentiation in lymphoid leukemia cell lines. These enzymatic activities may be useful markers for the differentiation of lymphoid leukemia cells.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 06:35:27