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Titolo:
IDENTIFICATION AND MANAGEMENT OF HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA - SUMMARY AND RECOMMENDATIONS FROM AN NHLBI WORKSHOP
Autore:
BILD DE; WILLIAMS RR; BREWER HB; HERD JA; PEARSON TA; STEIN E;
Indirizzi:
NHLBI,DECA,CLIN & GENET EPIDEMIOL BRANCH,7550 WISCONSIN AVE,ROOM 300 BETHESDA MD 20892 UNIV UTAH,CARDIOVASC GENET RES CLIN SALT LAKE CITY UT 84112 NHLBI,DIV INTRAMURAL RES,MOLEC DIS BRANCH BETHESDA MD 20892 BAYLOR COLL MED,DEPT MED HOUSTON TX 77030 COLUMBIA UNIV,MARY IMOGENE BASSETT RES INST COOPERSTOWN NY 00000 CHRIST HOSP,CARDIOVASC RES CTR CINCINNATI OH 45219
Titolo Testata:
The American journal of cardiology
fascicolo: 10, volume: 72, anno: 1993,
pagine: 40000001 - 40000005
SICI:
0002-9149(1993)72:10<40000001:IAMOHF>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
II HYPERLIPOPROTEINEMIA; HEART-DISEASE;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
D.E. Bild et al., "IDENTIFICATION AND MANAGEMENT OF HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA - SUMMARY AND RECOMMENDATIONS FROM AN NHLBI WORKSHOP", The American journal of cardiology, 72(10), 1993, pp. 40000001-40000005

Abstract

Heterozygous familial hypercholesterolemia (hFH) is one of the most common monogenic disorders with serious health consequences, affecting approximately 1 in 500 persons in the United States. Persons with hFH generally manifest elevations of low density lipoprotein (LDL) cholesterol throughout their lives and have a markedly increased risk of death from coronary artery disease. The hypercholesterolemia of hFH is responsive to medication and diet, and, if detected early, aggressive LDLcholesterol control may prevent or substantially delay cardiovasculardisease. However, evidence suggests that many persons with hFH are undetected and inadequately treated. On July 20-21, 1992, the National Heart, Lung, and Blood Institute sponsored a workshop to assess the current understanding of the diagnosis and management of hFH, to emphasize recommendations for identification and management that are known to be effective, and to identify opportunities and needs for interventionand research.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 15:20:20