Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
INTENSITY-RELATED CHANGES IN COCHLEAR BLOOD-FLOW IN THE GUINEA-PIG DURING AND FOLLOWING ACOUSTIC EXPOSURE
Autore:
SCHEIBE F; HAUPT H; LUDWIG C;
Indirizzi:
HUMBOLDT UNIV BERLIN,CHARITE,HNO KLIN,SCHUMANNSTR 20-21 D-10098 BERLIN GERMANY
Titolo Testata:
European archives of oto-rhino-laryngology
fascicolo: 5, volume: 250, anno: 1993,
pagine: 281 - 285
SICI:
0937-4477(1993)250:5<281:ICICBI>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
LASER DOPPLER MEASUREMENTS; LOUD SOUND EXPOSURE; CERVICAL SYMPATHECTOMY; DEOXYGLUCOSE UPTAKE; STIMULATION ALTERS; NOISE; VESSELS;
Keywords:
COCHLEAR BLOOD FLOW; LASER DOPPLER FLOWMETRY; ACOUSTIC EXPOSURE; COCHLEAR FUNCTION; GUINEA PIG;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
F. Scheibe et al., "INTENSITY-RELATED CHANGES IN COCHLEAR BLOOD-FLOW IN THE GUINEA-PIG DURING AND FOLLOWING ACOUSTIC EXPOSURE", European archives of oto-rhino-laryngology, 250(5), 1993, pp. 281-285

Abstract

This study examined the effects of acoustic exposure at different intensities on cochlear blood flow (CBF) using laser Doppler flowmetry. CBF was measured in anesthetized guinea pigs exposed to either a 10 kHzpure tone at 125, 105, or 90 dB SPL, or wide-band noise at 85 dB SPL for 1 h. Mean arterial blood pressure and heart rate were recorded continuously. Arterial acid-base status, cochlear temperature, cochlear microphonics (CM), and compound action potentials (CAP) were measured before and after exposure. There was a small, but significant, steady decline in basal CBF after 40 min loud sound exposure (125 dB SPL), butno change in basal CBF occurred with the lower intensities (85-105 dBSPL). In contrast, there was a significant increase in apical CBF after 1 h exposure to either moderate wide-band noise (85 dB SPL) or a 10kHz tone at 105 dB SPL. These changes persisted during a 20-min post-exposure period. In most cases, the cochlear temperature and cardiorespiratory variables monitored remained unchanged during and after the exposures as compared to the controls. CM and CAP amplitudes showed extensive losses after acoustic overstimulation (125 dB SPL), but no permanent changes were found at the lower intensities used. The present findings confirm the occurrence of intensity-related effects of acousticexposure on the cochlear microcirculation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 00:57:06