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Titolo:
CORRECTION FOR SCATTER IN 3D BRAIN PET USING A DUAL-ENERGY WINDOW METHOD
Autore:
GROOTOONK S; SPINKS TJ; SASHIN D; SPYROU NM; JONES T;
Indirizzi:
NEUROL INST,WELLCOME DEPT COGNIT NEUROL LONDON ENGLAND HAMMERSMITH HOSP,MRC,CYCLOTRON UNIT,CLIN SERV CTR LONDON W12 0NN ENGLAND UPMC,PET FAC PITTSBURGH PA 00000 UNIV SURREY,DEPT PHYS GUILDFORD GU2 5XH SURREY ENGLAND
Titolo Testata:
Physics in medicine and biology
fascicolo: 12, volume: 41, anno: 1996,
pagine: 2757 - 2774
SICI:
0031-9155(1996)41:12<2757:CFSI3B>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
RETRACTABLE SEPTA; TOMOGRAPHY; RECONSTRUCTION; SUBTRACTION; PHOTONS; CAMERA; SPECT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
S. Grootoonk et al., "CORRECTION FOR SCATTER IN 3D BRAIN PET USING A DUAL-ENERGY WINDOW METHOD", Physics in medicine and biology, 41(12), 1996, pp. 2757-2774

Abstract

A method for scatter correction using dual energy window acquisition has been developed and implemented on data collected with a brain-PET tomograph operated in the septa retracted, 3D mode. Coincidence eventsare assigned to (i) an upper energy window where both photons depositenergy between 380 keV and 850 keV or (ii) a lower energy window where one or both photons deposit within 200 keV and 380 keV. Scaling parameters are derived from measurements of the ratios of counts from linesources due to scattered and unscattered events in the two energy windows in head-sized phantoms. A scaled subtraction of the two energy windows produces a distribution of scatter which is smoothed prior to subtraction from the upper energy window. In phantoms, the correction was found to restore the uniformity, contrast and linearity of activity concentration. Relative activity concentrations were restored to within 7% of their true values in a multicompartment phantom. The method was found to provide accurate correction for scattered events arising from activity outside the direct detector field of view. In a three-compartment phantom containing water, F-18 and C-11 scanned in dynamic, multiframe mode, the half-lives of the two isotopes were restored to within 2% of their true value.

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Documento generato il 29/11/20 alle ore 15:18:29