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Titolo:
TUMOR VASCULARITY IN THE BRAIN - EVALUATION WITH DYNAMIC SUSCEPTIBILITY-CONTRAST MR-IMAGING
Autore:
MAEDA M; ITOH S; KIMURA H; IWASAKI T; HAYASHI N; YAMAMOTO K; ISHII Y; KUBOTA T;
Indirizzi:
FUKUI MED SCH,DEPT RADIOL,23 SHIMOAIZUKI FUKUI 91011 JAPAN FUKUI MED SCH,DEPT NEUROSURG FUKUI 91011 JAPAN
Titolo Testata:
Radiology
fascicolo: 1, volume: 189, anno: 1993,
pagine: 233 - 238
SICI:
0033-8419(1993)189:1<233:TVITB->2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
NECROSIS;
Keywords:
BRAIN NEOPLASMS; BRAIN NEOPLASMS, MR; CEREBRAL BLOOD VESSELS, FLOW DYNAMICS; GADOLINIUM; MAGNETIC RESONANCE (MR), CONTRAST ENHANCEMENT; MAGNETIC RESONANCE (MR), RAPID IMAGING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
13
Recensione:
Indirizzi per estratti:
Citazione:
M. Maeda et al., "TUMOR VASCULARITY IN THE BRAIN - EVALUATION WITH DYNAMIC SUSCEPTIBILITY-CONTRAST MR-IMAGING", Radiology, 189(1), 1993, pp. 233-238

Abstract

PURPOSE: To evaluate the efficacy of dynamic susceptibility-contrast magnetic resonance (MR) imaging for diagnosis of intraaxial brain tumors. MATERIALS AND METHODS: Ten patients with such tumors (two hemangioblastomas, five low-grade astrocytomas, and three glioblastomas) underwent examination at 1.5 T. After bolus injection of 0.15 mmol/kg gadopentetate dimeglumine, gradient-echo MR images were obtained every 3.6 seconds for 90 seconds. Region-of-interest analyses were performed in all tumors. RESULTS: The greatest loss in signal intensity during the first pass of the contrast agent was seen in hemangioblastomas; low-grade astrocytomas had the least loss. The differences in integration ofchange in the T2 relaxation rate were significant among the three types of tumor (hemangioblastomas vs low-grade astrocytomas, P < .001; hemangioblastomas vs glioblastomas, P < .005; and glioblastomas vs low-grade astrocytomas, P < .02) and indicated differences in vascularity. CONCLUSION: Dynamic susceptibility-contrast MR imaging can provide useful hemodynamic information about intraaxial brain tumors that is notprovided by standard MR imaging and therefore contributes to the differential diagnosis.

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Documento generato il 01/12/20 alle ore 16:43:55