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Titolo:
ONLINE REPOSITIONING DURING TREATMENT OF THE PROSTATE - A STUDY OF POTENTIAL LIMITS AND GAINS
Autore:
BALTER JM; CHEN GTY; PELIZZARI CA; KRISHNASAMY S; RUBIN S; VIJAYAKUMAR S;
Indirizzi:
UNIV MICHIGAN,UH-B2C490 BOX 0010,1500 E MED CTR DR ANN ARBOR MI 48109 UNIV CHICAGO,DEPT RADIAT & CELLULAR ONCOL CHICAGO IL 60637
Titolo Testata:
International journal of radiation oncology, biology, physics
fascicolo: 1, volume: 27, anno: 1993,
pagine: 137 - 143
SICI:
0360-3016(1993)27:1<137:ORDTOT>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
RADIATION-THERAPY; PORTAL IMAGES; RADIOTHERAPY;
Keywords:
IMAGE REGISTRATION; PRECISION RADIOTHERAPY; ONLINE IMAGING; SETUP ERROR; PATIENT REPOSITIONING;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
11
Recensione:
Indirizzi per estratti:
Citazione:
J.M. Balter et al., "ONLINE REPOSITIONING DURING TREATMENT OF THE PROSTATE - A STUDY OF POTENTIAL LIMITS AND GAINS", International journal of radiation oncology, biology, physics, 27(1), 1993, pp. 137-143

Abstract

Purpose: With on-line portal imaging devices and image registration tools, the verification of radiation field position Prior to each treatment becomes technically feasible. In this paper, we analyze the impact of pre-treatment verification and field position adjustment on target coverage and normal tissue sparing. Methods and Materials: Port films were compared with corresponding simulation films to determine the magnitude of setup variations in patients treated for prostate cancer. From these data, an analytic function was determined between geometriccoverage of the target and field margin size. A paradigm for on-line patient repositioning was employed to generate a new relationship between margin and target coverage. Margins were selected for the situations of normal treatment and on-line repositioning to ensure target coverage. Dose-volume histograms were generated for a typical prostate treatment using these margins. Results: On-line repositioning, when setuperrors exceed 1 cm, results in a 6 mm reduction in margin, suggestingthat 10% of the volume of bladder and rectum may be spared of high dose. Conclusion: The use of on-line imaging and image registration to guide adjustment of patient setup may lead to a eduction in the volume of normal tissues irradiated, and possibly improve the probability of complication-free survival in future treatments.

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Documento generato il 07/07/20 alle ore 12:43:30