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Titolo:
THEORETICAL-ANALYSIS OF GADOPENTETATE DIMEGLUMINE ENHANCEMENT IN T1-WEIGHTED IMAGING OF THE BRAIN - COMPARISON OF 2-DIMENSIONAL SPIN-ECHO AND 3-DIMENSIONAL GRADIENT-ECHO SEQUENCES
Autore:
MUGLER JP; BROOKEMAN JR;
Indirizzi:
UNIV VIRGINIA,HLTH SCI CTR,DEPT RADIOL,BOX 190,STACEY HALL,1105 W MAIN ST CHARLOTTESVILLE VA 22908
Titolo Testata:
Journal of magnetic resonance imaging
fascicolo: 5, volume: 3, anno: 1993,
pagine: 761 - 769
SICI:
1053-1807(1993)3:5<761:TOGDEI>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Keywords:
BRAIN, MR; BRAIN NEOPLASMS, MR; COMPARATIVE STUDIES; CONTRAST ENHANCEMENT; GADOLINIUM; MATHEMATICAL MODEL; PULSE SEQUENCES; 3-DIMENSIONAL IMAGING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
J.P. Mugler e J.R. Brookeman, "THEORETICAL-ANALYSIS OF GADOPENTETATE DIMEGLUMINE ENHANCEMENT IN T1-WEIGHTED IMAGING OF THE BRAIN - COMPARISON OF 2-DIMENSIONAL SPIN-ECHO AND 3-DIMENSIONAL GRADIENT-ECHO SEQUENCES", Journal of magnetic resonance imaging, 3(5), 1993, pp. 761-769

Abstract

By using a theoretical model, the signal difference-to-noise ratios between simulated lesions and normal white matter and gray matter were calculated as a function of lesion concentration of gadopentetate dimeglumine [GD] for two-dimensional [2D] T1-weighted spin-echo [SE], three-dimensional [3D] steady-state spoiled gradient-echo (GRE) (FLASH [fast low-angle shot]), and 3D magnetization-prepared rapid gradient echo[MP-RAGE] pulse sequences. The 3D GRE sequences provided greater contrast enhancement at relatively high [GD], and the 2D SE sequence demonstrated greater enhancement and a higher rate of enhancement at low [GD]. The results predict that at low [GD], certain lesions could probably be detected with the 2D SE sequence but possibly not with one or both of the 3D GRE sequences. At high [GD], certain lesions could probably be detected with one or both of the 3D GRE sequences but possibly not with the 2D SE sequence. This provides a potential explanation for the clinical observation that certain contrast agent-enhanced lesions appear less conspicuous on 3D GRE images than on 2D SE images and viceversa. Modified parameter values were derived for the 3D FLASH and 3DMP-RAGE sequences that are predicted to produce contrast enhancement behavior equivalent or superior to that of a conventional 2D SE sequence.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 01:25:23