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Titolo:
EFFECT OF TIME ON NEONATAL IMMUNE-RESPONSE TO DIETARY SELENIUM AND FAT
Autore:
HARIKKHAN R; SHAMSA F; JOHNSTON PV; PICCIANO MF; SEGRE M;
Indirizzi:
USDA ARS,BELTSVILLE AGR RES CTR,BARC E,BLDG 201,10300 BALTIMORE AVE BELTSVILLE MD 20705 UNIV ILLINOIS,DIV NUTR SCI URBANA IL 61801 UNIV ILLINOIS,COLL VET MED,DEPT PATHOBIOL URBANA IL 61801 GEORGE WASHINGTON UNIV,SCH MED WASHINGTON DC 20052 PENN STATE UNIV,DEPT NUTR UNIV PK PA 16802
Titolo Testata:
Journal of trace elements and electrolytes in health and disease
fascicolo: 2, volume: 7, anno: 1993,
pagine: 87 - 93
SICI:
0931-2838(1993)7:2<87:EOTONI>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLUTATHIONE-PEROXIDASE; VITAMIN-E; RATS; SUPPLEMENTATION; INFECTION; INVITRO; MICE; PARAMETERS; RADICALS; DISEASE;
Keywords:
SELENIUM; IMMUNE RESPONSE; NEONATAL RAT; ANTIBODY FORMATION; DIETARY FAT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
R. Harikkhan et al., "EFFECT OF TIME ON NEONATAL IMMUNE-RESPONSE TO DIETARY SELENIUM AND FAT", Journal of trace elements and electrolytes in health and disease, 7(2), 1993, pp. 87-93

Abstract

The effect of dietary selenium (0.03 mg/kg and 0.31 mg/kg), and fat (5% and 20% corn oil) on antibody formation in the neonatal rat was studied at two different time periods using four diets. The latter were fed to dams throughout pregnancy and lactation and to their pups starting at day 18. A week later, pups received intraperitoneal injections of the test antigen, fluorescein-bovine serum albumin in complete Freund's adjuvant (150 mug per 30 g body wt.). On days 7 or 9 post-injection, the pups were sacrificed. The antibody titer, as determined by the quenching of fluorescein by the test sera, and by ELISA, almost doubled from day 7 to day 9 (p < 0.05). There was no significant difference in antibody titers between dietary groups except at day 9 post-injection. Using ELISA, pairwise comparisons indicated that addition of 0.3 mg/kg Se to high fat diet was associated with low antibody titer (p < 0.05).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 20:16:42