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Titolo:
CARDIAC ADAPTATION TO INCREASED SYSTEMIC BLOOD-PRESSURE IN BORDERLINEHYPERTENSIVE MEN
Autore:
SUNG BH; LOVALLO WR; TEAGUE SM; PINCOMB GA; WILSON MF;
Indirizzi:
MILLARD FILLMORE HOSP,DEPT MED,3 GATES CIRCLE BUFFALO NY 14209 SUNY,DEPT MED BUFFALO NY 14260 UNIV OKLAHOMA HLTH SCI CTR,DEPT MED OKLAHOMA CITY OK 73190 UNIV OKLAHOMA HLTH SCI CTR,DEPT PSYCHIAT & BEHAV SCI OKLAHOMA CITY OK73190 VET AFFAIRS MED CTR OKLAHOMA CITY OK 00000
Titolo Testata:
The American journal of cardiology
fascicolo: 5, volume: 72, anno: 1993,
pagine: 407 - 412
SICI:
0002-9149(1993)72:5<407:CATISB>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXERCISE; RESISTANCE; STRESS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
B.H. Sung et al., "CARDIAC ADAPTATION TO INCREASED SYSTEMIC BLOOD-PRESSURE IN BORDERLINEHYPERTENSIVE MEN", The American journal of cardiology, 72(5), 1993, pp. 407-412

Abstract

The present study examined cardiac characteristics of borderline hypertensive men with a positive parental history of hypertension. Hemodynamics in relation to left ventricular function and structure were evaluated in 15 borderline hypertensive men with a parental history of hypertension and in 20 normotensive control subjects with a negative parental history. Groups were matched in age, height, weight and percent body fat. Left ventricular mass and dimensions were measured by M-mode echocardiography, and left ventricular function was assessed by radionuclide ventriculography. Both groups had similar left ventricular mass, dimensions and wall thicknesses. In relation to control subjects, borderline hypertensive men had a significantly higher heart rate and blood pressure (BP) (p < 0.001), but a similar cardiac index. Borderlinehypertensive men had a higher peripheral resistance index (p < 0.02),longer time to peak filling rate, and a reduced cardiac efficiency, whereas they had higher contractility, minute and stroke work indexes than did control subjects (all p < 0.05); they also had higher diastolic BP (p < 0.03) during exercise, and sustained higher BP during recovery than did controls. Although this group of borderline hypertensive men did not have an altered cardiac anatomy, they had an increased vascular resistance, an altered diastolic function and a reduced cardiac efficiency while undergoing a greater work load. These cardiodynamic profiles are consistent with functional vascular changes and a parallel compensation by the heart. It is concluded that increased cardiac output may not be a universal hemodynamic characteristic of all borderlinehypertensive subjects and that cardiac adjustments to increased BP may be secondary to vascular resistance changes in certain subgroups of borderline hypertensives, especially those with positive parental history of hypertension.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/10/20 alle ore 11:52:19