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Titolo:
LIGHT-MICROSCOPIC AUTORADIOGRAPHIC STUDY OF DNA-SYNTHESIS IN THE KIDNEYS OF AGING MICE
Autore:
HANAI T;
Indirizzi:
SHINSHU UNIV,SCH MED,DEPT ANAT & CELL BIOL MATSUMOTO NAGANO 390 JAPAN
Titolo Testata:
Cellular and molecular biology
fascicolo: 1, volume: 39, anno: 1993,
pagine: 81 - 91
SICI:
0145-5680(1993)39:1<81:LASODI>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROXIMAL TUBULE CELLS; RATS; PROLIFERATION; CULTURE; RENEWAL; ORIGIN;
Keywords:
MOUSE KIDNEY; DEVELOPMENT AND AGING; H-3-THYMIDINE; DNA SYNTHESIS; LIGHT MICROSCOPIC AUTORADIOGRAPHY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
T. Hanai, "LIGHT-MICROSCOPIC AUTORADIOGRAPHIC STUDY OF DNA-SYNTHESIS IN THE KIDNEYS OF AGING MICE", Cellular and molecular biology, 39(1), 1993, pp. 81-91

Abstract

The change of proliferative activity in mouse kidney cortex cells during development and aging was studied by detecting S-phase cells by light microscopic radioautography using H-3-thymidine (H-3-TDR). Mouse kidney tissues of various ages: prenatal 13.5, 15.5 and 19.0 days of gestation, postnatal 1 and 8 days, 1 and 2 months, and 1 year were used for this experiment. The kidney cortex tissues were labelled with H-3-TDR either in vitro or in vivo and they were processed for light microscopic radioautography. The labeling indices of the respective cell types were calculated. The labeling indices in glomeruli and uriniferoustubules in the superficial layer were higher than those in the deep layer of metanephric cortex through the developmental stages. However, they decreased rapidly after birth and reached low levels (below 4%) from 1 day to 1 year.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 22:15:00