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Titolo:
DETECTION OF HEPATIC METASTASES IN COLORECTAL-CANCER - A PROSPECTIVE-STUDY OF LABORATORY AND IMAGING METHODS
Autore:
OHLSSON B; TRANBERG KG; LUNDSTEDT C; EKBERG H; HEDERSTROM E;
Indirizzi:
LUND UNIV,DEPT SURG S-22101 LUND SWEDEN LUND UNIV,DEPT DIAGNOST RADIOL S-22101 LUND SWEDEN
Titolo Testata:
The European journal of surgery
fascicolo: 5, volume: 159, anno: 1993,
pagine: 275 - 281
SICI:
1102-4151(1993)159:5<275:DOHMIC>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIVER METASTASES; COMPUTED-TOMOGRAPHY; ADJUVANT THERAPY; PROXIMAL COLON; ULTRASONOGRAPHY; RECURRENCE; RESECTION; CARCINOMA; DIAGNOSIS; SITES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
B. Ohlsson et al., "DETECTION OF HEPATIC METASTASES IN COLORECTAL-CANCER - A PROSPECTIVE-STUDY OF LABORATORY AND IMAGING METHODS", The European journal of surgery, 159(5), 1993, pp. 275-281

Abstract

Objective: To assess and compare the accuracy of imaging methods (ultrasonography (US), computed tomography (CT), angiography, arterially enhanced CT with computed tomographic arterial portography (CTA)), biochemical analyses, and surgical assessment during the operation, in detecting the presence or absence of hepatic metastases in patients with colorectal cancer. Design: Open study. Setting: University of Lund, Sweden. Subjects: 71 consecutive patients without clinical evidence of liver metastases at the time of the operation for removal of the primary tumour. Interventions: Regular biochemical tests for five to seven years, and CT and US one year after operation in all patients without confirmed metastases. Main outcome measures: Presence or absence of hepatic metastases. Results: Accuracy of surgical assessment, angiography, US, CT and CTA was 90, 77, 80, 82 and 83%, respectively, and corresponding predictive values of a negative test were 87, 75, 77, 80 and 84%. Measurement of bilirubin concentration and hepatic enzyme activities were not helpful, and that of carcinoembryonic antigen had an accuracy of only 70%. Accuracy and predictive values were not improved by combining tests. Conclusion: The accuracy of US, CT or CTA was not good enough to merit routine use before operations for colorectal cancer. They are potentially valuable for monitoring progress at follow up, butthis remains to be confirmed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 05:37:53