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Titolo:
MRI EVALUATION OF MYOCARDIAL PERFUSION WITHOUT A CONTRAST AGENT USINGMAGNETIZATION-TRANSFER
Autore:
PRASAD PV; BURSTEIN D; EDELMAN RR;
Indirizzi:
BETH ISRAEL HOSP,CHARLES A DANA RES INST,DEPT RADIOL,330 BROOKLINE AVE BOSTON MA 02215 HARVARD UNIV,SCH MED BOSTON MA 02115
Titolo Testata:
Magnetic resonance in medicine
fascicolo: 2, volume: 30, anno: 1993,
pagine: 267 - 270
SICI:
0740-3194(1993)30:2<267:MEOMPW>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARTERIAL WATER; BRAIN; INVERSION; VOLUME; TIME;
Keywords:
MYOCARDIUM; PERFUSION; MAGNETIZATION TRANSFER; ISOLATED HEART;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
P.V. Prasad et al., "MRI EVALUATION OF MYOCARDIAL PERFUSION WITHOUT A CONTRAST AGENT USINGMAGNETIZATION-TRANSFER", Magnetic resonance in medicine, 30(2), 1993, pp. 267-270

Abstract

We propose a new magnetic resonance imaging (MRI) technique that is sensitive to myocardial tissue perfusion that obviates the use of an extrinsic contrast agent. Significant advantages of such a technique arethat it avoids accumulation of contrast agent when repeated studies are performed on the same subject and that it is completely noninvasive. The method makes use of a combination of magnetization transfer (MT)and T1sat (measured spin-lattice relaxation time in the presence of MT) weighting. In this Communication, we present observations from experiments with an isolated rat heart model that demonstrate increase of MT-weighted signal intensity and T1sat with flow. Also included are data showing that these effects can be made synergistic for enhancing the sensitivity to perfusion. We have observed about a 3% change in MT-weighted intensity and up to 10% change in MTT1sat-weighted intensity for a change of 1 ml/min in global flow rate.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 01:00:00