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Titolo:
DIAGNOSTIC COMPATIBILITY OF A THYMIDINE KINASE, INVERTED REPEAT, GI, AND GPX MODIFIED-LIVE GENE-DELETED PRV VACCINE WITH 3 DIFFERENTIAL ELISAS
Autore:
SWENSON SL; MCMILLEN J; HILL HT;
Indirizzi:
IOWA STATE UNIV SCI & TECHNOL,COLL VET MED,VET DIAGNOST LAB AMES IA 50011
Titolo Testata:
Journal of veterinary diagnostic investigation
fascicolo: 3, volume: 5, anno: 1993,
pagine: 347 - 350
SICI:
1040-6387(1993)5:3<347:DCOATK>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
S.L. Swenson et al., "DIAGNOSTIC COMPATIBILITY OF A THYMIDINE KINASE, INVERTED REPEAT, GI, AND GPX MODIFIED-LIVE GENE-DELETED PRV VACCINE WITH 3 DIFFERENTIAL ELISAS", Journal of veterinary diagnostic investigation, 5(3), 1993, pp. 347-350

Abstract

The differential pseudorabies virus (PRV) vaccines currently in use in the USA have deletions of the genes coding for the glycoprotein I (gI) and/or glycoprotein X (gpX). The absence of gI and/or gpX allow forthe serologic differentiation of vaccinated swine from PRV-infected swine using differential enzyme-linked immunosorbent assays (ELISAs). Anewly developed pseudorabies vaccine virus has 4 deletions of the viral genome: the genes coding for gI, gpX, and thymidine kinase and a portion of the repeat region to attenuate the virus. The purpose of thiswork was to evaluate the diagnostic compatibility of the gI/gpX gene-deleted vaccine with 3 differential vaccines and 3 differential ELISAscurrently in use. Pigs vaccinated 3 times with the gI/gpX gene-deleted vaccine remained seronegative on the 3 differential ELISAs tested. Pigs previously vaccinated with either a gI or gpX gene-deleted vaccineand then vaccinated with the gI/gpX gene-deleted vaccine remained seronegative on the respective gI or gpX differential assay.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 02:27:13