Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
LYMPHOCYTE HOMING RECEPTOR (CD44) EXPRESSION IS ASSOCIATED WITH POOR-PROGNOSIS IN GASTROINTESTINAL LYMPHOMA
Autore:
JOENSUU H; RISTAMAKI R; KLEMI PJ; JALKANEN S;
Indirizzi:
UNIV TURKU,CENT HOSP,DEPT ONCOL & RADIOTHERAPY SF-20520 TURKU 52 FINLAND UNIV TURKU,CENT HOSP,DEPT PATHOL SF-20520 TURKU 52 FINLAND NATL PUBL HLTH INST SF-20500 TURKU FINLAND
Titolo Testata:
British Journal of Cancer
fascicolo: 2, volume: 68, anno: 1993,
pagine: 428 - 432
SICI:
0007-0920(1993)68:2<428:LHR(EI>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
NON-HODGKINS-LYMPHOMA; HIGH ENDOTHELIUM; FLOW-CYTOMETRY; DISSEMINATION; RECOGNITION; MOLECULE; BINDING; ANTIGEN; TISSUE; LFA-1;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
H. Joensuu et al., "LYMPHOCYTE HOMING RECEPTOR (CD44) EXPRESSION IS ASSOCIATED WITH POOR-PROGNOSIS IN GASTROINTESTINAL LYMPHOMA", British Journal of Cancer, 68(2), 1993, pp. 428-432

Abstract

Lymphocyte homing receptor (CD44) is involved in lymphocyte adhesion to endothelial cells of high endothelial venules (HEVs) and lymphocyteexit from the blood circulation, and it may be involved also in hematogenous dissemination of malignant lymphoma. Prognostic significance of lymphocyte homing receptor expression defined by Hermes-3 antibody was studied among 27 gastrointestinal lymphomas followed up for 8 to 20years after the diagnosis. Lymphomas lacking or with very weak homingreceptor expression (n = 14, 52%) were associated with 57% 10-year survival rate as compared with only 15% among lymphomas that expressed CD44 more strongly (P = 0.02). We conclude that lack of lymphocyte homing receptor expression is common in gastrointestinal lymphoma, and that CD44 expression is associated with unfavourable prognosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 07:05:49